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(oncocytic change)
152 results
  • Succinate Dehydrogenase-Deficient Renal Cell Carcinoma. [Journal Article]
    Arch Pathol Lab Med 2019; 143(5):643-647Tsai TH, Lee WY
  • Succinate dehydrogenase (SDH)-deficient renal cell carcinoma is a recently recognized distinct subtype of renal cell carcinoma in the 2016 World Health Organization classification. It is associated with SDH gene germline mutations, which also cause paraganglioma/pheochromocytoma, gastrointestinal stromal tumor, and pituitary adenoma. The tumor most commonly presents in young adulthood. The tumors…
  • Psammomatoid Calcification-Rich Oncocytic Thyroid Adenoma With Clear-Cell Change. [Journal Article]
    Clin Pathol 2019 Jan-Dec; 12:2632010X19829251Handra-Luca A, Belleannee G, Straub B
  • Abundant calcifications and clear-cell change may occur in oncocytic thyroid adenoma (OTA). We aimed to report the features of a case of OTA peculiar by the presence of extensive calcifications and of a clear-cell component. The OTA was detected on a right thyroid lobectomy specimen. Clear-cell change was observed in 15%-20% of the cells. Numerous, focally confluent psammomatoid calcifications, r…
  • Clear Cell Variant of a Follicular Thyroid Tumor With Uncertain Malignant Potential: A Case Report. [Journal Article]
    Int J Surg Pathol 2019; 27(3):290-293Juhlin CC, Bränström R, … Höög A
  • Follicular neoplasms of the thyroid gland are most often characterized by follicular-patterned thyrocytes with a neutrally stained cytoplasm, while a minority of cases present with oncocytic differentiation (Hürthle cell tumors). Exceedingly rare variants with a clear cell phenotype have also been reported, both as clear cell follicular thyroid adenomas (ccFTAs) and clear cell follicular carcinom…
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