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165,806 results
  • [Progress in HIV-1 Env trimer design]. [Review]
    Sheng Wu Gong Cheng Xue Bao 2020; 36(1):25-32Shen H, Zhang Z, … Gu Y
  • Currently, HIV-1 vaccine development has still been a hot pot in the AIDS research. HIV-1 glycoprotein Env is the sole target in the virion surface that mediates the membrane fusion between the virion and cell in the HIV-1 infection process. Env protein is the significant immunogen for HIV-1 vaccine development. In recent years, there have been breakthroughs in the Env trimer research. For exampl…
  • [HIV/AIDS related frailty syndrome in the elderly and related research progress]. [Journal Article]
    Zhonghua Liu Xing Bing Xue Za Zhi 2020; 41(1):127-130Tan H, Wu WZ, … Zeng H
  • Frailty syndrome, caused by degenerative changes in the body and the body vulnerability due to a variety of chronic diseases, is associated with adverse outcomes, such as fall, disability and mortality. With the development of antiretroviral therapy, the average life span of HIV/AIDS patients is extended, the number of elderly living with HIV/AIDS has increased, resulting the increase of the inci…
  • [Assessment of data quality of intervention in population at high risk for HIV/AIDS in China, 2014-2018]. [Journal Article]
    Zhonghua Liu Xing Bing Xue Za Zhi 2020; 41(1):85-89Li L, Luo W, … Rou KM
  • Objective: To assess the quality of data of intervention in population at high risk for HIV/AIDS, especially in female sex workers (FSWs) and men who have sex with men (MSM), in China during 2014-2018, for the purpose of improving intervention data quality. Methods: Data accuracy was evaluated by sampling monthly reported intervention data and comparing the consistency of the information record…
  • [Characteristics and dynamics of HIV-1 subtype distribution among injected drug users in Guangzhou, 2008 - 2015]. [Journal Article]
    Zhonghua Liu Xing Bing Xue Za Zhi 2019; 40(12):1629-1633Zhao YT, Han ZG, … Xu HF
  • Objective: To understand the characteristics and dynamics of individuals with HIV-1 subtype infection among injected drug users (HIV infection IDU) in Guangzhou between 2008 and 2015. Methods: HIV-1 RNAs were extracted from serum samples of the individuals that were newly diagnosed with HIV-1 infection among IDUs living in Guangzhou, between 2008 and 2015. The Pol gene segments of HIV-1 genome …
  • Outbreak of Listeriosis in South Africa Associated with Processed Meat. [Journal Article]
    N Engl J Med 2020; 382(7):632-643Thomas J, Govender N, … Blumberg LH
  • CONCLUSIONS: This investigation showed that in a middle-income country with a high prevalence of HIV infection, L. monocytogenes caused disproportionate illness among pregnant girls and women and HIV-infected persons. Whole-genome sequencing facilitated the detection of the outbreak and guided the trace-back investigations that led to the identification of the source.
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