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(oogenesis)
9,983 results
  • Comparing DNA damage induced by mobile telephony and other types of man-made electromagnetic fields. [Review]
    Mutat Res 2019 Jul - Sep; 781:53-62Panagopoulos DJ
  • The number of studies showing adverse effects on living organisms induced by different types of man-made Electromagnetic Fields (EMFs) has increased tremendously. Hundreds of peer reviewed published studies show a variety of effects, the most important being DNA damage which is linked to cancer, neurodegenerative diseases, reproductive declines etc. Those studies that are far more effective in sh…
  • Role of p53 isoforms in the DNA damage response during Drosophila oogenesis. [Journal Article]
    Sci Rep 2019; 9(1):11473Park JH, Nguyen TTN, … Song YH
  • The tumor suppressor p53 is involved in the DNA damage response and induces cell cycle arrest or apoptosis upon DNA damage. Drosophila p53 encodes two isoforms, p53A and p53B, that induce apoptosis in somatic cells. To investigate the roles of Drosophila p53 isoforms in female germline cells, the DNA damage response was analyzed in the adult ovary. Early oogenesis was sensitive to irradiation and…
  • Yes-associated protein expression in germ cells is dispensable for spermatogenesis in mice. [Letter]
    Genesis 2019; :e23330Abou Nader N, Levasseur A, … Boyer A
  • Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is expressed in the nucleus of spermatogonia in mice, suggesting a potential role in spermatogenesis. Here, we report the generation of a conditional knockout mouse model (Yapflox/flox ; Ddx4cre/+) that specifically inactivates Yap in the germ cells. The inactivation of Yap in spermatogonia was found to be highly efficie…
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