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417 results
  • Hepatopulmonary Syndrome in a Thirteen Year Old Boy: A Case Report. [Case Reports]
    Cureus 2019; 11(8):e5295Shahid M, Tameez Ud Din A, … Tameez-Ud-Din A
  • Hepatopulmonary syndrome (HPS) is a late complication associated with liver cirrhosis. Recent studies have suggested that it can also occur in non-cirrhotic portal hypertension. The criteria that need to be met for making the diagnosis of HPS include chronic liver disease, impaired gaseous exchange leading to hypoxemia and intrapulmonary vascular dilation. The pathophysiology of this disease incl…
  • Interstitial pneumonia with autoimmune features and platypnea-orthopnea syndrome. [Journal Article]
    BMJ Case Rep 2019; 12(9)Mathew U, Mittal A, … Ray A
  • Interstitial pneumonia with autoimmune features (IPAF) is a recently proposed terminology for interstitial lung disease (ILD) with evidence of autoimmunity that does not meet the criteria for a defined connective tissue disease (CTD). Although ILD is well recognised in patients with established CTD, it is rarely the sole presenting feature of CTD. We report a case of 22-year-old male patient, who…
  • Postural nausea due to platypnea orthodeoxia. [Journal Article]
    BMJ Support Palliat Care 2019Bradley V, Sabharwal N, … Bond C
  • Platypnea orthodeoxia is an uncommon condition but given its associations with severe lung disease and advancing age, it might be seen in the palliative care population. Presentation is classical in the association of symptoms with postural change. It should be considered when patients present with breathlessness or desaturation given the minimally invasive tests of echocardiography, and the pote…
  • Paralytic ileus precipitating platypnoea-orthodeoxia after right pneumonectomy. [Journal Article]
    Eur J Cardiothorac Surg 2019Whiteley J, Lynn P, … Butler J
  • A 78-year-old female underwent a right pneumonectomy for a neuroendocrine tumour. In the early postoperative phase, she developed a paralytic ileus and went on to develop breathlessness and orthostatic desaturation, which characterizes platypnoea-orthodeoxia. She was found to have an intra-atrial shunt on bubble echo, with equal atrial pressures. This was managed by device closure of the atrial c…
  • Platypnoea-orthodeoxia syndrome after pulmonary lobectomy: a rare entity with a difficult diagnosis. [Journal Article]
    Interact Cardiovasc Thorac Surg 2019Krasas A, Tzifa A, … Iliadis K
  • Platypnoea-orthodeoxia syndrome (POS) is a rare clinical entity. It is characterized by position-dependent dyspnoea and oxygen desaturation in the upright position with orthodeoxia resolving in the supine position, and is mainly associated with cardiac defects. Only 9 cases of post-lobectomy POS have been reported in the literature. We describe a case of POS in a woman who underwent a lobectomy a…
  • "Liver or Let Die": Percutaneous PFO Closure Through Hepatic Vein Access. [Journal Article]
    Heart Lung Circ 2019; 28(10):e134-e136Stehli J, Michail M, … Harper R
  • A 73-year-old farmer presented with platypnoea-orthodeoxia syndrome (POS). A transoesophageal echocardiogram (TOE) disclosed a patent foramen ovale (PFO) with significant right-to-left shunt on assuming upright posture. An initial attempt at PFO closure through the femoral vein was abandoned due to a completely occluded inferior vena cava. A second attempt through the internal jugular vein was al…
  • Patent foramen ovale and ascending aortic aneurysm causing the platypnea-orthodeoxia syndrome. [Case Reports]
    Proc (Bayl Univ Med Cent) 2019; 32(2):242-244Agdamag AC, Gomez JM, … Kavinsky C
  • Patent foramen ovale (PFO) is present in about 25% of the population. Platypnea-orthodeoxia syndrome (POS), which is dyspnea and hypoxemia in the upright position that is relieved when supine, is a rare manifestation of PFO. We describe a case of a 74-year-old woman who presented with new-onset hypoxia. A PFO and a dilated aorta causing POS were found on workup. Symptoms were resolved after under…
  • Platypnoea-orthodeoxia syndrome: beware of investigations undertaken supine. [Journal Article]
    Thorax 2019; 74(9):917-919Liew F, Gargoum F, … Polkey MI
  • Platypnoea-orthodeoxia syndrome (POS) is a rare disorder, manifesting as deoxygenation occurring when the patient is in the upright position. Four broad mechanisms for the condition have been described: intracardiac shunts, intrapulmonary shunts, hepatopulmonary syndrome and pulmonary ventilation-perfusion mismatch. Here, we present the first case of POS in a patient with a proven right to left i…
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