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19,100 results
  • Clinical outcomes of pallidal deep brain stimulation for dystonia implanted using intraoperative MRI. [Journal Article]
    J Neurosurg 2019; :1-13Sharma VD, Bezchlibnyk YB, … Gross RE
  • CONCLUSIONS: Intraoperative MRI-guided lead placement in patients with dystonia showed improvement in clinical outcomes comparable to previously reported results using awake MER-guided lead placement. The accuracy of lead placement was high, and the procedure was well tolerated in the majority of patients. However, a number of patients experienced serious adverse events that were attributable to the introduction of a novel technique into a busy neurosurgical practice, and which led to the revision of protocols, product inserts, and on-site training.
  • Genetic and environmental influences on corticostriatal circuits in twins with autism [Journal Article]
    J Psychiatry Neurosci 2019; 44(6):190030Hegarty II JP, Lazzeroni LC, … Hardan AY
  • CONCLUSIONS: Genetic factors primarily contribute to structural variation in subcortical CSC regions, regardless of ASD, but environmental factors may exert a greater influence on the development of grey matter thickness in the OFC and ACC in children with ASD. The increased vulnerability of OFC grey matter to environmental influences may also mediate some heterogeneity in RRB severity in children with ASD.
  • Age-Dependent Signal Intensity Changes in the Structurally Normal Pediatric Brain on Unenhanced T1-Weighted MR Imaging. [Journal Article]
    AJNR Am J Neuroradiol 2019Flood TF, Bhatt PR, … Mirsky DM
  • CONCLUSIONS: Age-dependent signal intensity values were determined on unenhanced T1WI in structurally normal pediatric brains. Increased age correlated with increased signal intensity in all brain locations, except the frontal gray matter, irrespective of sex. The biologic mechanisms underlying our results remain unclear and may be related to chronologic changes in myelin density, synaptic density, and water content. Establishing age-dependent signal intensity parameters in the structurally normal pediatric brain will help clarify developmental aberrations and enhance gadolinium-deposition research by providing an improved understanding of the confounding effect of age.
  • Mean diffusivity associated with trait emotional intelligence. [Journal Article]
    Soc Cogn Affect Neurosci 2019Takeuchi H, Taki Y, … Kawashima R
  • Previous neuroimaging studies have suggested that the neural bases of trait emotional intelligence (TEI) lie in the social cognition network (SCN) and the somatic marker circuitry (SMC). The current study is the first to investigate the associations of total TEI factors and subfactors with mean diffusivity (MD) of these networks as well as regional MD of the dopaminergic system (MDDS). We found t…
  • Subcortical Volume Changes in Migraine with Aura. [Journal Article]
    J Clin Neurol 2019; 15(4):448-453Petrusic I, Dakovic M, Zidverc-Trajkovic J
  • CONCLUSIONS: These findings suggest that both the globus pallidi and left putamen play significant roles in the pathophysiology of the MwA. Future studies should determine the cause-and-effect relationships, since these could not be discriminated in this study due to its cross-sectional design.
  • Basal ganglia volume and shape in anorexia nervosa. [Journal Article]
    Appetite 2019; 144:104480Leppanen J, Cardi V, … Tchanturia K
  • CONCLUSIONS: The present findings appear to fit with the theoretical models suggesting that there are alterations in the basal ganglia regions associated with habit formation and reward processing in AN. Further investigation of structural and functional connectivity of these regions in AN as well as their role in recovery would be of interest.
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