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149,538 results
  • StatPearls: Tracheal Injury [BOOK]
    StatPearls Publishing: Treasure Island (FL) Farley Loyal S. LS Carl R Darnall Army Medical Center Schlicksup Kevin E. KE Carl R. Darnall Army Medical Center BOOK
  • The trachea is a tube-like structure beginning at the base of the cricoid cartilage and extending to the carina. It has cervical and thoracic portions, separated at the level of the thoracic inlet above and below respectively. It includes 18 to 22 D-shaped rings which are cartilaginous anteriorly and laterally and membranous posteriorly. Blood supply to the cervical portions of the trachea comes …
  • StatPearls: Intellectual Disability [BOOK]
    StatPearls Publishing: Treasure Island (FL) Lee Keun K Aventura Hospital and Medical Center Cascella Marco M Istituto Nazionale Tumori - IRCCS - Fondazione Pascale, Via Mariano Semmola 80100, Napoli. Italy Marwaha Raman R Case Western Reserve Un/MetroHealth MC BOOK
  • Individuals with an intellectual disability have neurodevelopmental deficits characterized by limitations in intellectual functioning and adaptive behavior. These disabilities originate and manifest before the age of 18 and can be associated with a considerable number of related and co-occurring problems including mental health (e.g., depression, and anxiety), neurodevelopmental (e.g., autism spe…
  • Microglia in developing white matter and perinatal brain injury. [Review]
    Neurosci Lett 2019; :134539McNamara NB, Miron VE
  • Perinatal brain injury (PBI) to the developing white matter results in hypomyelination of axons and can cause long-term motor and cognitive deficits e.g. cerebral palsy. There are currently no approved therapies aimed at repairing the white matter following insult, underscoring the need to investigate the mechanisms underlying the pathogenesis of PBI. Microglia have been strongly implicated, but …
  • Toilet Training: Common Questions and Answers. [Journal Article]
    Am Fam Physician 2019; 100(8):468-474Baird DC, Bybel M, Kowalski AW
  • Toilet training is a significant developmental milestone in early childhood. Most U.S. children achieve the physiologic, cognitive, and emotional development necessary for toilet training by 18 to 30 months of age. Markers of readiness for toilet training include being able to walk, put on and remove clothing, and follow parental instruction; expressive language; awareness of a full bladder or re…
  • Muscle Synergies in Response to Biofeedback-Driven Gait Adaptations in Children With Cerebral Palsy. [Journal Article]
    Front Physiol 2019; 10:1208Booth ATC, van der Krogt MM, … Buizer AI
  • CONCLUSIONS: These results suggest that while gait may be adapted in an immediate response, SMC as quantified by synergy analysis is perhaps more rigidly impaired in CP. Subtle changes in synergies were identified; however, it is questionable if these are clinically meaningful at the level of an individual. Adaptations may be limited in the short term, and further investigation is essential to establish if long term training using biofeedback leads to adapted SMC.
  • Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats. [Journal Article]
    Front Pharmacol 2019; 10:1131Ceprián M, Vargas C, … Martínez-Orgado J
  • Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects neurons and glial cells after HI insult in newborn animals. We hereby aimed to study CBD's effects on long-lasting HI-induced myelination deficits in newborn rats. Thus, P7 Wistar rats received s.c. vehicle (HV) or cannabidiol (HC) after HI brain damage (left c…
  • Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis. [Review]
    Cell Death Dis 2019; 10(10):782Cao C, Yu M, Chai Y
  • Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host response to infection that leads to uncontrolled inflammatory response followed by immunosuppression. However, despite the high mortality rate, no specific treatment modality or drugs with high efficacy is available for sepsis to date. Although improved treatment strategies have increased the survival rate during …
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