- Clinical features of childhood uveitis at a tertiary referral center in Southern Turkey. [Journal Article]
- CONCLUSIONS: Pediatric uveitis is a challenging disease that requires meticulous management. Anterior uveitis is the most frequent form. Despite a changing trend for an increase in diagnostic variety, idiopathic cases still constitute the majority. A significant number of patients receive systemic therapy, develop complications, and require surgical intervention. Early diagnosis and appropriate treatment might improve visual outcomes and reduce the risk of visual loss.
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- Clinical Course and Treatment Paradigms for JIA-related Uveitis and Pars Planitis Uveitis Using Precise Ocular Investigational Methods. [Journal Article]Klin Monbl Augenheilkd. 2021 Feb 19 [Online ahead of print]KM
- CONCLUSIONS: Nowadays, new investigational techniques have made precise follow-up of uveitis possible. We determined the precise inflammatory pattern of JIA uveitis and PP, which is crucial information to determine the therapeutic intervention. As these two entities are common in young and paediatric patients, such precise monitoring is essential to determine adequate treatment paradigms and avoid unnecessary systemic treatment, especially corticosteroids. When the ophthalmic status requires it, multidisciplinary collaboration between the ophthalmologist, the paediatrician and the rheumatologist may be needed to offer optimal management to the patient. In cases of purely ocular involvement, it is the ophthalmologist who should determine the management.
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- Retinoblastoma in an older Hispanic child masquerading as pars planitis: A case report. [Journal Article]Eur J Ophthalmol. 2021 Feb 10 [Online ahead of print]EJ
- CONCLUSIONS: Given the rare incidence of retinoblastoma in children older than 5 years old, it can be easily mistaken for other differential diagnoses and treated with filtration surgeries that could put the patient's life at risk. In this report, late-onset Rb diagnosis is highlighted as a differential diagnosis in children and adults with atypical uveitis, which required a multidisciplinary approach.
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- Spectral domain optical coherence tomography findings of patients with pars planitis and risk factors affecting visual acuity. [Journal Article]
- CONCLUSIONS: DME and loss of normal foveal contour appearance were more likely to have adverse effects on visual acuity.
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- Imbalance in PB IL-17-Secreting and Regulatory Cells in Pars Planitis Is Associated with Dysregulation of IFN-γ-Secreting Cells, Especially in Patients with Clinical Complications. [Journal Article]
- CONCLUSIONS: In pars planitis, the alterations in lymphocyte cell distribution affect primarily the T cell repertoire. The imbalance in PB Th1/Th17/Treg cells creates proinflammatory conditions, strengthening the suggestion that the immune background may play a role in pars planitis pathogenesis. Also, circulating Th1 level may be of potential clinical relevance in terms of prediction of a more severe course of the disease.
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- Pediatric Uveitis in a Referral Center in North Part of Turkey. [Journal Article]Ocul Immunol Inflamm. 2020 May 28 [Online ahead of print]OI
- CONCLUSIONS: The most common localization was the anterior segment and the most common etiologic relationship was JIA. Visual outcome could be satisfactory with early and appropriate treatment.
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- Implications of pars planitis-associated cystoid macular edema on visual outcome and management in children. [Journal Article]
- CONCLUSIONS: Pars planitis-associated CME entailed higher prevalence of ocular complications, more frequent use of immunomodulatory therapy, and a lower rate of remission.
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- A Cross-Sectional Online Survey Identifies Subspecialty Differences in the Management of Pediatric Cataracts Associated with Uveitis. [Journal Article]
- CONCLUSIONS: Pediatric ophthalmologists and uveitis ophthalmologists have similar approaches to the management of pediatric uveitic cataract removal and IOL insertion, but several differences remain between these subspecialties. Continued collaboration between the subspecialties would be helpful to better develop consistent criteria to improve patient care.
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- Characterization of cyclitic membranes by ultrabiomicroscopy in patients with pars planitis. [Journal Article]
- CONCLUSIONS: UBM is a valuable tool for the diagnosis of cyclitic membranes at admittance and during follow-up of patients with pars planitis; it helps the clinician to detect this complication early.
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- StatPearls: Chorioretinitis [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Chorioretinitis is a type of uveitis involving the posterior segment of the eye, which includes inflammation of the choroid and the retina of the eye. Though the term uveitis means inflammation of the uveal tract (iris, ciliary body, and choroid), it can involve the adjacent structures like the retina, retinal vessels, vitreous, optic nerve head, and sclera. The Standardization of Uveitis Nomencl…
- Comparison of Methods of Endotamponade Used During 23-Gauge Pars Plana Vitrectomy and the Risk of Raised Intraocular Pressure During 24-Month Follow-Up: A Retrospective Study of 196 Patients. [Journal Article]
- CONCLUSIONS: Silicone oil endotamponade in PPV was associated with an increased risk of IOP at 24-month follow-up.
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- The Clinical Characteristics of Pediatric Non-Infectious Uveitis in Two Tertiary Referral Centers in Turkey. [Journal Article]Ocul Immunol Inflamm. 2019 Nov 05 [Online ahead of print]OI
- CONCLUSIONS: Most pediatric noninfectious uveitis cases have bilateral intermediate uveitis. JIA was the most common systemic association. The first-year VA was good in most eyes which may be due to early use of corticosteroid-sparing agents.
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- Inferior Corneal Haze and Inflammatory Endotheliopathy Related to Pars Planitis. [Journal Article]Ocul Immunol Inflamm. 2020 Jul 03; 28(5):798-801.OI
- CONCLUSIONS: Inferior posterior corneal haze related to inflammatory endotheliopathy may occur in eyes with pars planitis. As patients with pars planitis may be otherwise asymptomatic, this corneal finding shouldprompt a detailed funduscopic examination to rule out this form of uveitis.
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- Clinical Presentation, Management, and Long-Term Outcome of Pars Planitis, Panuveitis, and Vogt-Koyanagi-Harada Disease in Children and Adolescents. [Journal Article]Arthritis Care Res (Hoboken). 2020 11; 72(11):1589-1596.AC
- CONCLUSIONS: PP, PU, and VKH involve a high risk of permanent vision loss and should be managed by a skilled rheumatologist as early and as aggressively as possible.
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- Clinical and etiologic characteristics of de novo uveitis in patients aged 60 years and above: experience of a French tertiary center. [Journal Article]
- CONCLUSIONS: In our center, sarcoidosis is the leading cause of non-idiopathic uveitis in older patients. Idiopathic uveitis and other entities account for less than two-thirds of cases. Ophthalmologic entities are rare after 60 years of age. We also report for the first time the characteristics of uveitis after 70 years of age.
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- Successful treatment with infliximab after adalimumab failure in pediatric noninfectious uveitis. [Journal Article]J AAPOS. 2019 06; 23(3):151.e1-151.e5.JA
- CONCLUSIONS: In our study cohort, infliximab was used successfully in all cases of recalcitrant pediatric noninfectious uveitis that previously failed adalimumab therapy.
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- Visual and Clinical Outcome of Macular Edema Complicating Pediatric Noninfectious Uveitis. [Multicenter Study]
- CONCLUSIONS: The prognosis of pediatric uveitic ME is favorable despite its chronic course. Larger randomized controlled trials are needed to define differences among treatment regimens.
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- Progression of retinal pigmentation mimicking unilateral retinitis pigmentosa after bilateral pars planitis: a case report. [Case Reports]
- CONCLUSIONS: An inflammatory disease like pars planitis can accelerate the pigmentation of the retina and mimic a RP in young patients. Causes of pseudoRP may be considered, especially in those rare cases with unilateral affection.
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- Association of giant retinal tear with iridofundal coloboma in a case of paediatric retinal detachment. [Case Reports]
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- Bilateral cystoid macular edema misdiagnosed as pars planitis in a patient on sertraline therapy. [Case Reports]
- CONCLUSIONS: Development of cystoid macular edema due to sertraline is a very rare adverse event and must be considered by psychiatrists and ophthalmologists. Our case demonstrates this rare toxicity along with its imaging features, and reversal on cessation of sertraline therapy.
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- Complications in Intermediate Uveitis: Prevalence, Time of Onset, and Effects on Vision in Short-Term and Long-Term Follow-Up. [Multicenter Study]
- CONCLUSIONS: IU is a chronic low-grade uveitis that may be associated with protean early and late complications of the anterior or posterior segments or both. Optimal treatment regimens are imperative for the strict control of inflammation and proper management of complications thus allowing a favorable long-term prognosis.
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- Red-eyed-tatoo: An unusual red eye of tuberculous etiology. [Case Reports]Arch Soc Esp Oftalmol. 2018 Jun; 93(6):e43.AS
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- Child With Red Eye and Blurry Vision. [Case Reports]Pediatr Emerg Care. 2017 Oct; 33(10):703-705.PE
- Point-of-care ocular ultrasound can provide the clinician with more information about potential intraorbital and extraocular pathology, especially in cases when direct visualization of the eye is limited. This case report describes the findings in a pediatric patient who presented with a 1-month history of eye injection and worsening blurry vision. After point-of-care ultrasound demonstrated abno…
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- Patterns of Intermediate Uveitis in Children Presenting at a Tertiary Eye Care Center in South India. [Journal Article]
- CONCLUSIONS: Median time of development of complications is about 3 years based on our study. Intermediate uveitis of childhood might exhibit a self-limiting course after several years. Visual recovery is good in the majority, and visual loss is limited despite the high rate of ocular complications.
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- StatPearls: Pars Planitis [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Pars planitis is chronic intermediate uveitis for which no systemic disease or associated infection could be found. The term intermediate uveitis describes an intraocular inflammatory process with vitreous as the primary site of inflammation. Inflammation may be present in the anterior vitreous, the vitreous base overlying the peripheral retina-pars plana region. It is characterized by vitreal in…
- Challenges with cataract surgery in pars planitis patients. [Editorial]
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- Managing multiple caterpillar hair in the eye. [Case Reports]
- Ophthalmia nodosa with vitreoretinal involvement is rare and may cause permanent loss of eye due to persistent inflammation of the eye. A young female patient having multiple caterpillar hair in the eye including cornea, anterior chamber, sclera, and pars plana presented with recurrent vitritis and pars planitis. Ultrasound biomicroscopy played a vital role and helped in localizing the hair embed…
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- Outcomes of cataract surgery with/without vitrectomy in patients with pars planitis and immunosuppressive therapy. [Journal Article]
- CONCLUSIONS: Phacoemulsification was the procedure for all the patients. Visual acuity improved in patients with pars planitis treated with immunosuppressive drugs who underwent cataract surgery, except for the patients with posterior segment complications or amblyopia.
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- Analysis of clinical features and visual outcomes of pars planitis. [Journal Article]
- CONCLUSIONS: Pars planitis is an idiopathic chronic intermediate uveitis mostly affecting children and adolescents. In spite of its chronic nature with high potential of causing ocular complications, adequate treatment and close follow-up lead to favorable visual outcomes.
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- Unilateral uveitis associated with IgA nephropathy. [Case Reports]Arch Soc Esp Oftalmol. 2017 Dec; 92(12):598-601.AS
- CONCLUSIONS: Uveitis and glomerulonephritis may have common immunological pathogenesis. IgA nephropathy should be a differential diagnosis in patients with uveitis and nephropathy.
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