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28,254 results
  • Vitamin D in Triple-Negative and BRCA1-Deficient Breast Cancer-Implications for Pathogenesis and Therapy. [Review]
    Int J Mol Sci. 2020 May 23; 21(10)Blasiak J, Pawlowska E, … Chojnacki C
  • Several studies show that triple-negative breast cancer (TNBC) patients have the lowest vitamin D concentration among all breast cancer types, suggesting that this vitamin may induce a protective effect against TNBC. This effect of the active metabolite of vitamin D, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D), can be attributed to its potential to modulate proliferation, differentiation, apoptosis, i…
  • Bisphosphonate Therapy and Tooth Development in Children and Adolescents with Osteogenesis Imperfecta. [Journal Article]
    Calcif Tissue Int. 2020 May 25 [Online ahead of print]Malmgren B, Tsilingaridis G, … Åström E
  • Osteogenesis imperfecta (OI) is a heterogeneous connective tissue disorder characterized by repeated fractures and skeletal disorders. At present, bisphosphonate (BP) therapy is the gold standard for OI treatment. The present retrospective study evaluated the effect of BP therapy on tooth development and eruption of permanent teeth in a cohort of children receiving pamidronate. Three groups were …
    Kidney Int. 2020 May 21 [Online ahead of print]DeLalio LJ, Masati E, … Isakson BE
  • Kidney function and blood pressure homeostasis are regulated by purinergic signaling mechanisms. These autocrine/paracrine signaling pathways are initiated by the release; of cellular ATP, which influences kidney hemodynamics and steady-state renin secretion; from juxtaglomerular cells. However, the mechanism responsible for ATP release that supports tonic inputs to juxtaglomerular cells and regu…
  • Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome. [Journal Article]
    Pediatr Neurol. 2020 Apr 13 [Online ahead of print]Lewis H, Samanta D, … Zarate YA
  • CONCLUSIONS: Epileptiform abnormalities are commonly seen in individuals with SATB2-associated syndrome. A baseline electroencephalography that preferably includes sleep stages is recommended during the initial evaluation of all individuals with SATB2-associated syndrome, regardless of clinical suspicion of epilepsy.
  • Impact of asthma on children´s gustatory sensitivity, masticatory and feeding behaviors. [Journal Article]
    Physiol Behav. 2020 May 20 [Online ahead of print]Cj AG, DA P, … Pm C
  • Asthma is a chronic inflammatory disease, in which disturbances in breathing, masticatory and swallowing functions may impact the eating behavior. The aim of the study was to evaluate the impact of asthma on taste sensitivity, masticatory behavior and feeding problems in children. The sample consisted of 91 children (6-7y) divided into two groups: asthma (n=46) and control group (n=45). Interview…
  • Age and Upper Airway Obstruction: A Challenge to the Clinical Approach in Pediatric Patients. [Journal Article]
    Int J Environ Res Public Health. 2020 May 18; 17(10)Luana N, Marco Z, … Massimo A
  • Upper airway abnormalities increase the risk of pediatric morbidity in infants. A multidisciplinary approach to obstructive sleep apnea syndrome (OSAS) poses challenges to clinical practice. The incidence and causes of OSA are poorly studied in children under 2 years of age. To fill this gap, we performed this retrospective observational study to determine the causes of obstructive sleep apnea (O…
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