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(penicilloyl polylysine)
92 results
  • Evaluating Penicillin Allergies Without Skin Testing. [Review]
  • CACurr Allergy Asthma Rep 2019 Mar 22; 19(5):27
  • Banks TA, Tucker M, Macy E
  • An unconfirmed penicillin allergy is known to confer significant risk to patients. Only a small minority of patients labeled with penicillin allergy will be confirmed to be hypersensitive with the cu…
  • Penicillin minor determinants: History and relevance for current diagnosis. [Review]
  • AAAnn Allergy Asthma Immunol 2018; 121(5):537-544
  • Adkinson NF, Mendelson LM, … Keogh JC
  • CONCLUSIONS: IgE skin testing, using both the major and appropriate minor determinants of penicillin, can identify, with a high degree of reliability (NPV ∼97%), penicillin allergy history-positive patients who can receive beta-lactam antibiotics without concern for serious acute allergy, including anaphylaxis. The few false-negative skin tests reported globally are largely confined to minor, self-limited cutaneous reactions.
  • A Proactive Approach to Penicillin Allergy Testing in Hospitalized Patients. [Journal Article]
  • JAJ Allergy Clin Immunol Pract 2017 May - Jun; 5(3):686-693
  • Chen JR, Tarver SA, … Khan DA
  • CONCLUSIONS: Penicillin allergy testing using a physician-pharmacist team model effectively removes reported allergies in hospitalized patients. The electronic medical record is a valuable asset for locating and stratifying individuals who benefit most from intervention. Proactive testing substantially reduces unnecessary inpatient and outpatient use of beta-lactam alternatives that may otherwise go unaddressed.
  • Skin testing with β-lactam antibiotics for diagnosis of β-lactam hypersensitivity in children. [Clinical Trial]
  • APAsian Pac J Allergy Immunol 2016; 34(3):242-247
  • Manuyakorn W, Singvijarn P, … Jotikasthira W
  • CONCLUSIONS: Among those children with a history of β-lactam hypersensitivity, skin testing with penicillin G, ampicillin, amoxicillin-clavulanic acid, and the suspect β-lactam was safe and provided a good NPV when PPL and MDM were unavailable. However, a skin test with β-lactam antibiotics alone did not provide a high sensitivity, thus a DPT procedure was necessary in order to confirm the diagnosis of β-lactam hypersensitivity.
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