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3,009 results
  • Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis. [Review]
    Pharmacol Res 2019; :104447Pisanu C, Franconi F, … Agabio R
  • There are conflicting results about sex differences in the response to opioids for pain control and the role of potential influencing factors of these differences has not been investigated. We meta-analyzed differences and similarities between men and women in opioid response for pain control and investigated the potential influence of baseline pain intensity, age, body weight, and other factors …
  • Local complications of pentazocine abuse: Case report and review. [Case Reports]
    Ind Psychiatry J 2018 Jul-Dec; 27(2):296-301Kumar S, Chaudhury S, … Kumari R
  • The skin is the tissue most commonly affected by intravenous drug addiction with pentazocine. The present article attempts to review the adverse effects of injecting drug use along with one case report of cutaneous complications of injection pentazocine abuse underlining the need for early identification, management, and above all prevention. It also provides credence to the fact that pentazocine…
  • Allosteric Modulators of Sigma-1 Receptor: A Review. [Review]
    Front Pharmacol 2019; 10:223Vavers E, Zvejniece L, … Dambrova M
  • Allosteric modulators of sigma-1 receptor (Sig1R) are described as compounds that can increase the activity of some Sig1R ligands that compete with (+)-pentazocine, one of the classic prototypical ligands that binds to the orthosteric Sig1R binding site. Sig1R is an endoplasmic reticulum membrane protein that, in addition to its promiscuous high-affinity ligand binding, has been shown to have cha…
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