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1,966 results
  • Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines. [Journal Article]
    Naunyn Schmiedebergs Arch Pharmacol 2019; 392(10):1257-1264Otręba M, Pajor M, Warncke JD
  • Cutaneous melanoma is least common (only about 1% of skin cancers) but is the deadliest malignant tumor. Moreover, amelanotic types of melanoma are very difficult for clinical diagnosis. The standard therapy can cause a lot of side effects, e.g., nausea, vomiting, and headaches, which means that novel and effective strategies are required. Interestingly, phenothiazine derivatives possess sedative…
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