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1,257 results
  • Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cells. [Journal Article]
    J Pineal Res 2019; 67(4):e12610Kleszczyński K, Kim TK, … Slominski AT
  • Melanogenesis is a key parameter of differentiation in melanocytes and melanoma cells; therefore, search for factors regulating this pathway are strongly desired. Herein, we investigated the effects of melatonin, a ubiquitous physiological mediator that is found throughout animals and plants. In mammals, the pineal gland secretes this indoleamine into the blood circulation to exert an extensive r…
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