- Management of Polycythemia Vera: A Survey of Canadian Physician Practice Patterns. [Journal Article]Clin Lymphoma Myeloma Leuk 2019; 19(1):e37-e42CL
- CONCLUSIONS: The survey confirmed that heterogeneity of practice in diagnosis and management of PV among Canadian hematologists exists, suggesting that targeted education in specific segments of the PV treatment providers may result in wider adoption of the guidelines and diagnostic criteria.
- [CTLs induced by hTERT-related multiepitope peptide-sensitived mDCs specifically kill HLA-A24+ tumor cells]. [Journal Article]Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2011; 27(6):626-30XB
- CONCLUSIONS: mDCs-impulsed with hTERT-associated MAPs can induce production and proliferation of allogenic CTLs, which show antigen specific anti-tumor effect against HLA-A24(+) tumor cells. This result has significantly meaning in tumor immunotherapy.
- Cyanotic congenital heart disease (CCHD) with symptomatic erythrocytosis. [Case Reports]J Gen Intern Med 2007; 22(12):1775-7JG
- Secondary erythrocytosis of cyanotic congenital heart disease (CCHD) is pathologically different from primary erythrocytosis of polycythemia vera (PV). An association between elevated hematocrit and thrombosis has been established in PV patients, and treatment guidelines recommend maintaining hematocrit <45%. Although an association between elevated hematocrit and thrombosis has not been establis…
Secondary erythrocytosis of cyanotic congenital heart disease (CCHD) is pathologically different from primary erythrocytosis of polycythemia vera (PV). An association between elevated hematocrit and thrombosis has been established in PV patients, and treatment guidelines recommend maintaining hematocrit <45%. Although an association between elevated hematocrit and thrombosis has not been established in CCHD and secondary erythrocytosis, the current clinical practice is to phlebotomize these patients to hematocrit <65%. We report a 21-year-old woman with CCHD who presented with symptomatic erythrocytosis with numbness and tingling with hemoglobin 25.2 g/dl and hematocrit 75.8%. Her symptoms resolved with IV hydration. Other factors, including dehydration and iron deficiency, may precipitate hyperviscosity symptoms. The treatment is volume replacement and low-dose iron therapy, not phlebotomy. Repeated phlebotomy causes iron deficiency with microcytic erythrocytes, which increases the whole blood viscosity and, therefore, can potentially accentuate rather than decrease the risk for a cerebrovascular accident.
- Autologous blood transfusion in patients with placenta previa. [Journal Article]Acta Obstet Gynecol Scand 2005; 84(3):255-9AO
- CONCLUSIONS: The program of autologous blood collection and transfusion in patients with placenta previa resulted in a decrease in homologous blood transfusion. In our program, we recommend starting blood collection and storage at 32 weeks' gestation and phlebotomize 400 ml per week to reach a volume of stored blood of 1200-1500 ml.
- [Measurement of cerebral blood oxygen saturation with near infrared spectroscopy and its application in hypergravity]. [Journal Article]Space Med Med Eng (Beijing) 2003; 16(5):371-3SM
- CONCLUSIONS: Oxygen saturation of blood in the rat's brain can be obtained non-invasively with near infrared spectroscopy.