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20,015 results
  • Rapid Production of Physiologic Dendritic Cells (phDC) for Immunotherapy. [Journal Article]
    Methods Mol Biol 2020; 2097:173-195Hanlon D, Sobolev O, … Edelson RL
  • Generation of large numbers of dendritic cells (DC) for research or immunotherapeutic purposes typically involves in vitro conversion of murine bone marrow precursors or human blood monocytes to DC via cultivation with supraphysiologic concentrations of cytokines such as GM-CSF and IL-4 for up to 7 days. Alternatively, our group has recently established a new approach, based on the underlying mec…
  • Treatment Of Nail Lichen Planus With Localized Bath-PUVA. [Letter]
    Photodermatol Photoimmunol Photomed 2019Pita da Veiga G, Pérez-Feal P, … Rodríguez-Granados MT
  • Lichen planus (LP) is an inflammatory condition usually involving the skin, hair, and mucous membranes. Nail involvement is present in 10-25% of patients and it is a diagnostic and therapeutic challenge. A 52-year-old female, Fitzpatrick skin type III, diagnosed of dyslipidemia and alopecia areata twenty years earlier, treated with intralesional corticosteroids, presented to our Phototherapy Unit…
  • The Science and (Lost) Art of Psoralen Plus UVA Phototherapy. [Review]
    Dermatol Clin 2020; 38(1):11-23Richard EG
  • PUVA phototherapy is the therapeutic use of psoralens and UVA light to treat inflammatory skin diseases, with psoriasis the prototype disease. Naturally occurring phototoxic compounds, psoralens interact with UVA to suppress DNA synthesis and cell proliferation and induce apoptosis of inflammatory cells. Well-developed therapeutic protocols for psoriasis guide psoralen and UVA doses, treatment fr…
  • Indocyanine green loaded APTMS coated SPIONs for dual phototherapy of cancer. [Journal Article]
    J Photochem Photobiol B 2019; 201:111648Bilici K, Muti A, … Yagci Acar H
  • Superparamagnetic iron oxide nanoparticles (SPIONs) have been recently recognized as highly efficient photothermal therapy (PTT) agents. Here, we demonstrate, for the first time to our knowledge, dose and laser intensity dependent PTT potential of small, spherical, 3-aminopropyltrimethoxysilane coated cationic superparamagnetic iron oxide nanoparticles (APTMS@SPIONs) in aqueous solutions upon irr…
  • Task-Specific Design of Immune-Augmented Nanoplatform to Enable High-Efficiency Tumor Immunotherapy. [Journal Article]
    ACS Appl Mater Interfaces 2019; 11(46):42904-42916Zhang J, Zhang D, … Luan Y
  • Potentiating systemic immunity against breast cancer is in the most urgent demand as breast cancer is less sensitive to immune checkpoint blockade. Although phototherapy and some chemotherapy can trigger immunogenic cell death (ICD) for T cell-mediated antitumor immune response, their immunotherapy efficacy is severely restricted by insufficient phototherapeutic capability and severe multidrug re…
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