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3,230 results
  • A child with Gradenigo syndrome presenting with meningism: a case report. [Journal Article]
    BMC Pediatr 2019; 19(1):350Athapathu AS, Bandara ERS, … Mettananda S
  • CONCLUSIONS: This case report highlights the importance of a thorough physical examination in children presenting with unrelated neurological symptoms and signs. Unilateral abducens nerve palsy raises the suspicion of increased intracranial pressure and neuroimaging is vital in diagnostic uncertainties. Gradenigo syndrome emphasises the importance of incorporating anatomical knowledge into clinical practice.
  • Delayed-Onset Transient Light Sensitivity Syndrome after Corneal Collagen Cross-Linking: A Case Series. [Journal Article]
    Med Hypothesis Discov Innov Ophthalmol 2019; 8(3):250-256Moshirfar M, Vaidyanathan U, … Hoopes PC
  • In this case series, we report a potentially novel association of corneal collagen crosslinking (CCL) with the development of photophobia symptoms in a series of patients at a tertiary ophthalmology clinic and describe their clinical course. Photosensitivity is a rare and seemingly unpredictable complication of refractive surgery but can present as a disabling, bilateral ocular pain that requires…
  • Understanding the Role of Pro-resolving Lipid Mediators in Infectious Keratitis. [Journal Article]
    Adv Exp Med Biol 2019; 1161:3-12Berger EA
  • Keratitis is a sight-threatening inflammatory condition of the cornea that can be caused by both infectious and non-infectious agents. Physical or chemical trauma are typically related to non-infectious keratitis, which may then become secondarily infected or remain non-infected. Etiology of infectious keratitis is most often associated with bacteria; but viruses, fungi, and parasites are common …
  • CGRP-based Migraine Therapeutics: How Might They Work, Why So Safe, and What Next? [Journal Article]
    ACS Pharmacol Transl Sci 2019; 2(1):2-8Russo AF
  • Migraine is a debilitating neurological condition that involves the neuropeptide calcitonin gene-related peptide (CGRP). An exciting development is the recent FDA approval of the first in an emerging class of CGRP-targeted drugs designed to prevent migraine. Yet despite this efficacy, there are some fundamental unanswered questions, such as where and how CGRP works in migraine. Preclinical data s…
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