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(physostigmine salicylate)
156 results
  • Behavioral and biochemical evidences for nootropic activity of boldine in young and aged mice. [Journal Article]
    Biomed Pharmacother 2018; 97:895-904Dhingra D, Soni K
  • Boldine, a bioactive compound, has been reported to be neuroprotective, but its effect on learning and memory has not been explored. So, the present study was aimed to study the effect of boldine on the learning and memory of the Swiss albino male young and aged mice. Boldine (1.5, 3 and 6mg/kg, po) and physostigmine salicylate (0.1mg/kg, ip) were administered to separate groups of mice for 7 suc…
  • Development and optimization of a sublingual tablet formulation for physostigmine salicylate. [Journal Article]
    Acta Pharm 2009; 59(3):301-12Bolourchian N, Hadidi N, … Shafaghi B
  • This study is aimed to design and optimize a sublingual tablet formulation of physostigmine salicylate, an effective drug in Alzheimer's disease and nerve gas poisoning, by means of the D-optimal experimental design methodology. Polyvinyl pyrrolidone, lactose, starch 1500 and sodium starch glycolate were used in the formulations as independent variables. Tablets were prepared by the direct compre…
  • Subacute atropine toxicity in a pygmy sperm whale, Kogia breviceps. [Case Reports]
    J Zoo Wildl Med 2002; 33(1):66-72Manire CA, Byrd L, … Smith DR
  • Atropine, an anticholinergic agent commonly used in human and veterinary medicine, is reported to cause toxicity associated with its antimuscarinic action. A juvenile pygmy sperm whale, Kogia breviceps, was treated with atropine in an attempt to relieve symptoms similar to pyloric stenosis, as has been used in humans. Two doses of 0.01 mg/kg were given i.m., 12 hr apart, followed by three doses o…
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