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(phytonadione)
1,755 results
  • Vitamin K-what is known regarding bariatric surgery patients: a systematic review. [Journal Article]
    Surg Obes Relat Dis 2019; 15(8):1402-1413Sherf-Dagan S, Goldenshluger A, … Ben-Porat T
  • Vitamin K, a fat-soluble vitamin, is involved in blood coagulation, bone mineralization, inhibition of vascular calcification, and regulation of numerous enzyme systems. Patients who undergo bariatric surgery (BS), especially procedures that involve a malabsorptive component, are prone to develop vitamin K deficiency (VKD). The causes of VKD include decreased absorptive surface areas, steatorrhea…
  • Quantitation of vitamin K1 in serum using online SPE-LC-MS/MS and the challenges of working with vitamin K. [Journal Article]
    J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1117:41-48Boegh Andersen I, Lohman Brasen C, … Schmedes A
  • Vitamin K1 (phylloquinone) is one of the vitamin Ks. Several studies have previously investigated the role of vitamin K1 status in respect to disease, but without consistent results. Since vitamin K deficiency has been associated with different disease states it is important to develop a biochemical analysis with sufficient sensitivity and a low limit of quantitation (LOQ). The vitamin Ks are ver…
  • Modelling electron transfer in photosystem I: limits and perspectives. [Journal Article]
    Physiol Plant 2019; 166(1):73-87Santabarbara S, Casazza AP, Hastings G
  • Uncovering the parameters underlying the electron transfer (ET) in photosynthetic reaction centres is of importance for understanding the molecular mechanisms underpinning their functionality. The reductive nature of most cofactors involved in photosynthetic ET makes the direct estimation of their properties difficult. Photosystem I (PSI) operates in a highly reducing regime, making the assessmen…
  • Effects of Obesity on Warfarin Reversal With Vitamin K. [Journal Article]
    Clin Appl Thromb Hemost 2019 Jan-Dec; 25:1076029618824042Luc SA, Whitworth MM, King SE
  • Phytonadione (vitamin K1, VK) is fat soluble and may be sequestered by adipose tissue, thus potentially altering drug distribution in obese patients requiring warfarin reversal. This single-center retrospective cohort study aimed to determine the effects of obesity (defined as body mass index [BMI] ≥ 30 kg/m2) on warfarin reversal following administration of VK in adult patients. The primary outc…
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