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7,823 results
  • Pathogenicities of Rice Blast (Pyricularia oryzae Cavara) Isolates From Kenya. [Journal Article]
    Plant Dis 2019; :PDIS04190870REFukuta Y, Telebanco-Yanoria MJ, … Makihara D
  • A total of 99 isolates of rice blast (Pyricularia oryzae Cavara) were collected from 2010 to 2015 from four regions in Kenya: Kirinyaga County and Embu County, Kisumu County, Tana River County, and Mombasa County. The pathogenicities of these isolates were clarified based on the reaction patterns of Lijiangxintuanheigu and differential varieties (DVs) targeting 23 resistance genes. The frequency …
  • Role of Heat Shock Proteins in Glaucoma. [Review]
    Int J Mol Sci 2019; 20(20)Tsai T, Grotegut P, … Joachim SC
  • Glaucoma, one of the most common causes of blindness worldwide, is a multifactorial neurodegenerative disease characterized by damage of retinal ganglion cells and optic nerve degeneration. However, the exact mechanism leading to glaucoma is still not understood. Evidences suggest an immunological involvement in the pathogenesis. Among other immune responses, altered autoantibody patterns were fo…
  • Oxidative pathways of arachidonic acid as targets for regulation of platelet activation. [Review]
    Prostaglandins Other Lipid Mediat 2019; :106382Trostchansky A, Moore-Carrasco R, Fuentes E
  • Platelet activation plays an important role in acute and chronic cardiovascular disease states. Multiple pathways contribute to platelet activation including those dependent upon arachidonic acid. Arachidonic acid is released from the platelet membrane by phospholipase A2 action and is then metabolized in the cytosol by specific arachidonic acid oxidation enzymes including prostaglandin H synthas…
  • Anticipating a future versus integrating a recent event? Evidence from eye-tracking. [Journal Article]
    Acta Psychol (Amst) 2019; 200:102916Abashidze D, Carminati MN, Knoeferle P
  • When comprehending a spoken sentence that refers to a visually-presented event, comprehenders both integrate their current interpretation of language with the recent event and develop expectations about future event possibilities. Tense cues can disambiguate this linking, but temporary ambiguity in these cues may lead comprehenders to also rely on further, experience-based (e.g., frequency or an …
  • Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging. [Journal Article]
    JCI Insight 2019; 4(20)Mazur C, Powers B, … Verma A
  • Intrathecal (IT) delivery and pharmacology of antisense oligonucleotides (ASOs) for the CNS have been successfully developed to treat spinal muscular atrophy. However, ASO pharmacokinetic (PK) and pharmacodynamic (PD) properties remain poorly understood in the IT compartment. We applied multimodal imaging techniques to elucidate the IT PK and PD of unlabeled, radioactively labeled, or fluorescent…
  • Breast cancer stem cells: The role of sex steroid receptors. [Review]
    World J Stem Cells 2019; 11(9):594-603Giovannelli P, Di Donato M, … Castoria G
  • Breast cancer (BC) is the most common cancer among women, and current available therapies often have high success rates. Nevertheless, BC might acquire drug resistance and sometimes relapse. Current knowledge about the most aggressive forms of BC points to the role of specific cells with stem properties located within BC, the so-called "BC stem cells" (BCSCs). The role of BCSCs in cancer formatio…
  • Stem Cell-Derived Extracellular Vesicles and Kidney Regeneration. [Review]
    Cells 2019; 8(10)Grange C, Skovronova R, … Bussolati B
  • Extracellular vesicles (EVs) are membranous vesicles containing active proteins, lipids, and different types of genetic material such as miRNAs, mRNAs, and DNAs related to the characteristics of the originating cell. They possess a distinctive capacity to communicate over long distances. EVs have been involved in the modulation of several pathophysiological conditions and, more importantly, stem …
  • StatPearls: Anatomy, Back, Spinal Meninges [BOOK]
    StatPearls Publishing: Treasure Island (FL) Sehgal Imran I Florida International University M Das Joe J National Hospital for Neurology and Neurosurgery, Queen Square, London BOOK
  • The spinal cord and brain are encased within three layers of tissue called the meninges. The spinal meninges specifically enclose the spinal cord and stretch from the brainstem down to the filum terminale. The layers of the meninges are, from deep to superficial, the pia mater, the arachnoid mater, and the dura mater. The names of these layers give information on their qualities. Pia, which is La…
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