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(pneumococcidal)
22 results
  • Ascorbate modulates antibacterial mechanisms in experimental pneumococcal pneumonia. [Journal Article]
    Am Rev Respir Dis 1986; 133(4):643-7Esposito AL
  • To evaluate the influence of vitamin C on pulmonary antibacterial mechanisms, normal CD-1 mice were administered sodium ascorbate (200 mg/kg/24 h) and challenged intratracheally with type 3 Streptococcus pneumoniae. Survival rates were similar in ascorbate-treated and control animals. When infected with a high inoculum (1 X 10(6) cfu), animals given vitamin C demonstrated a significant enhancemen…
  • Digoxin disrupts the inflammatory response in experimental pneumococcal pneumonia. [Journal Article]
    J Infect Dis 1985; 152(1):14-23Esposito AL
  • Digoxin was administered to normal CD-1 mice (4 micrograms/kg per 24 hr), and the mice were inoculated intratracheally with Streptococcus pneumoniae in order to assess the effects of the cardiac glycoside on pulmonary antibacterial mechanisms. Digoxin-treated animals experienced a worse survival rate than did controls (19 of 50 versus 33 of 50; P less than .01). When challenged with a high inocul…
  • CHANGES IN THE TITER OF ANTIPNEUMOCOCCAL HUMORAL IMMUNITY IN ADULT HUMAN BEINGS. [Journal Article]
    J Exp Med 1933; 58(2):245-52Graeser JB, Harrison MC
  • Fifty-five individuals were tested to determine the pneumococcidal promoting activity of their serum against Types I and II pneumococci. By repeated tests an attempt was made to study the constancy of the degree of their immunity over intervals of 2 to 6 months. In this group were included nine persons with common colds and twelve cases of a severe influenza-like infection. Fifteen of the fifty-f…
  • IMMUNITY REACTIONS OF HUMAN SUBJECTS TO STRAINS OF PNEUMOCOCCI OTHER THAN TYPES I, II AND III. [Journal Article]
    J Exp Med 1933; 57(1):95-109Finland M, Sutliff WD
  • 1. A group of 72 human subjects were studied with respect to the immune reactions of their blood and sera to Types I, II and III pneumococci and to 4 other types (V, VI, VIII and IX) previously included in Group IV. 2. The same general relationships were observed for all of these types as were previously demonstrated for Types I, II and III. Each type was specific in relation to the bactericidal …
  • ANTIPNEUMOCOCCIC IMMUNITY REACTIONS IN INDIVIDUALS OF DIFFERENT AGES. [Journal Article]
    J Exp Med 1932; 55(6):837-52Sutliff WD, Finland M
  • 1. The incidence of pneumococcidal power of the whole defibrinated blood in human beings has been shown to vary with age. The age distribution of other type-specific antibodies varies similarly, insofar as they are frequent enough to be compared or technically demonstrable. 2. The incidence of pneumococcidal power of the whole defibrinated blood for Type I, Type II, and Type III differs. Type I i…
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