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(pregneninolone)
241 results
  • Microbial transformation ethisterone by Aspergillus niger and Cunninghamella blakesleeana. [Journal Article]
    Steroids 2019; :108467Aziz A, Bano S, … Iqbal Choudhary M
  • Ethisterone (17α-ethynyl-17β-hydroxyandrost-4-en-3-one) (1) is a synthetic steroidal estrogen. It is extensively used as an oral contraceptive. The current study involves biotransformation of ethisterone (1) by Aspergillus niger, and Cunninghamella blakesleeana. Fermentation of 1 with C. blakesleeana afforded two new polar metabolites 17α-ethynyl-6β,15β,17β-trihydroxyandrost-4-en-3-one, 17α-ethyn…
  • Presence of emerging contaminants in urban water bodies in southern Brazil. [Journal Article]
    J Water Health 2019; 17(2):329-337Ghesti Pivetta G, do Carmo Cauduro Gastaldini M
  • The presence of pharmaceutical and hormone residues in water bodies is a matter of recent global concern. This study investigated the presence of such contaminants in two urban water bodies located in the city of Santa Maria, in southern Brazil. Two urban catchments, characterized by anthropogenic influences and poor household waste collection and treatment systems, were investigated. The Cancela…
  • Steroid-AuI -NHC Complexes: Synthesis and Antibacterial Activity. [Journal Article]
    ChemMedChem 2017; 12(11):841-844Vellé A, Maguire R, … Montagner D
  • A series of gold(I) pioneer complexes bearing N-heterocyclic carbenes and steroid derivatives (ethynylestradiol and ethisterone) with the generic formula [Au(R2 -imidazol-2-ylidene)(steroid)] (where R=CH3 or CH2 CH2 OCH3 ) were synthesized, and the X-ray structure of a rare of gold(I)-estradiol derivative is discussed. Toxicity studies reveal notable antibacterial activity of the gold-based compo…
  • A Silver(I)-Estrogen Nanocluster: GSH Sensitivity and Targeting Suppression on HepG2 Cell. [Journal Article]
    Small 2016; 12(44):6153-6159Shen DF, Wu SS, … Gao GG
  • A structure-determined silver nanocluster of [Ag10 (Eth)4 (CF3 COO)6 (CH3 OH)3 ]·3C-H3 OH (Eth = ethisterone) (1), is firstly demonstrated by self-assembly of silver salt and ethisterone. Due to the thiophilicity of silver(I) ions, complex 1 shows reactivity with glutathione (GSH) molecules in solution and induces the fluorescence quenching behavior. Thus, complex 1 can be used as a fluorescent s…
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