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6,872 results
  • Circulating molecular biomarkers for screening or early diagnosis of colorectal cancer: which is ready for prime time? [Review]
    Ann Transl Med 2019; 7(21):610Danese E, Montagnana M, Lippi G
  • According to recent statistics, colorectal cancer (CRC) is a frequent disease, the second most frequent malignancy in women and the third most common malignant disease in men, respectively. Although reinforced emphasis on CRC screening by means of immunochemical fecal occult blood test, colonoscopy or sigmoidoscopy has contributed to decrease cancer-related deaths, alternative diagnostic tests wo…
  • Cost-utility of colorectal cancer screening at 40 years old for average-risk patients. [Journal Article]
    Prev Med 2020; :106003Azad NS, Leeds IL, … Padula WV
  • The incidence of colorectal cancer (CRC) is increasing in patients under the age of 50. The purpose of this study was to assess the cost-utility of available screening modalities starting at 40 years in the general population compared to standard screening at 50 years old. A decision tree modeling average-risk of the CRC in the United States population was constructed for the cost per quality-adj…
  • A proposed tailored investigational algorithm for women treated for gynaecological cancer with long-term gastrointestinal consequences. [Journal Article]
    Support Care Cancer 2020Muls A, Taylor A, … Andreyev HJ
  • CONCLUSIONS: Women with gastrointestinal symptoms after cancer treatment benefit from a systematic management approach. After excluding disease recurrence, a proposed investigational algorithm and the oncology team includes FBC, U&Es, LFTs, thyroid function test, vitamin B12, vitamin D, a hydrogen methane breath test and a SeHCAT scan. If rectal bleeding is present, iron studies, flexible sigmoidoscopy or colonoscopy should be performed. Patients with normal investigations or symptoms not responding to treatment require gastroenterology input.
  • The Impact of Team-Based Primary Care on Guideline-Recommended Disease Screening. [Journal Article]
    Am J Prev Med 2020Fiset-Laniel J, Diop M, … Strumpf EC
  • CONCLUSIONS: This study found no evidence that Family Medicine Groups affected screening rates for these 3 chronic diseases. Limitations in the implementation of the Family Medicine Group policy in its early years may have contributed to this lack of impact. Interprofessional primary care teams may need to include elements other than organizational changes to increase disease prevention efforts.
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