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Unbound Medicine.
(progressive pterygium)
59 results
  • Xeroderma Pigmentosum: A Model for Human Premature Aging. [Review]
    J Invest Dermatol. 2021 Jan 09 [Online ahead of print]Rizza ERH, DiGiovanna JJ, … Kraemer KH
  • Aging results from intrinsic changes (chronologic) and damage from external exposures (extrinsic) on the human body. The skin is ideal to visually differentiate their unique features. Inherited diseases of DNA repair, such as xeroderma pigmentosum (XP), provide an excellent model for human aging due to the accelerated accumulation of DNA damage. Poikiloderma, atypical lentigines, and skin cancers…
  • Ryanodine receptor 1-related disorders: an historical perspective and proposal for a unified nomenclature. [Review]
    Skelet Muscle. 2020 Nov 16; 10(1):32.Lawal TA, Todd JJ, … Dirksen RT
  • The RYR1 gene, which encodes the sarcoplasmic reticulum calcium release channel or type 1 ryanodine receptor (RyR1) of skeletal muscle, was sequenced in 1988 and RYR1 variations that impair calcium homeostasis and increase susceptibility to malignant hyperthermia were first identified in 1991. Since then, RYR1-related myopathies (RYR1-RM) have been described as rare, histopathologically and clini…
  • Biomarkers of inflammation and oxidative stress in ophthalmic disorders. [Review]
    J Immunoassay Immunochem. 2020 May 03; 41(3):257-271.Ahmad A, Ahsan H
  • The review article focuses on free radicals and oxidative stress involved in ophthalmological diseases such as retinopathy, cataract, glaucoma, etc. Oxidative stress is considered as a key factor involved in the pathology of many chronic diseases including ophthalmic complication and inflammatory process. Oxidative stress and inflammation are closely related pathophysiological processes and are s…
  • Clinical Aspects of Pterygium in the Presence of Cataract. [Case Reports]
    Curr Health Sci J. 2019 Jul-Sep; 45(3):263-271.Mercuţ Nicolcescu MF, Crăiţoiu Ș, … Ionescu M
  • Two of the most common UV-induced eye affections are pterygium and cataract. They are both defined as progressive diseases that impair patients' vision and share some common elements in their evolution process. The purpose of this study was to determine whether the presence of cataract influences the clinical signs and symptoms of patients with pterygium. Therefore, we have analyzed 84 patients w…
  • Toric intraocular lens in asymmetric astigmatism. [Journal Article]
    Int Ophthalmol. 2020 May; 40(5):1291-1298.Kwitko S, Marafon SB, Stolz AP
  • CONCLUSIONS: The favorable efficacy on visual acuity outcomes we have found suggests that toric IOL can be used in cases of asymmetric astigmatism, in order to provide better-corrected vision, less spectacles dependence and an improved quality of vision overall, which is especially important in contact lenses intolerant patients.
  • [Pterygium: etiology, pathogenesis, treatment]. [Review]
    Vestn Oftalmol. 2017; 133(5):76-83.Malozhen SA, Trufanov SV, Krakhmaleva DA
  • Pterygium is a degenerative condition characterized by fibrovascular outgrowth of conjunctiva over the cornea. Many theories exist that try to explain its pathogenesis. The current belief is that this disease is multifactorial with ultraviolet radiation being the most important trigger. Attention is also paid to such factors as tear film changes, cytokines and growth factors disbalance, immunolog…
  • Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery. [Review]
    Cochrane Database Syst Rev. 2016 12 02; 12:CD011308.Romano V, Cruciani M, … Fontana L
  • CONCLUSIONS: The meta-analyses, conducted on people with pterygium in a hospital or outpatient setting, show fibrin glue may result in less recurrence and may take less time than sutures for fixing the conjunctival graft in place during pterygium surgery. There was low-certainty evidence to suggest a higher proportion of complications in the fibrin glue group.
  • Escobar (multiple pterygium) syndrome: Multidisciplinary approach to a very rare syndrome. [Case Reports]
    Eklem Hastalik Cerrahisi. 2016 Dec; 27(3):171-4.Sözbilen MC, Günay H, Çalış FA
  • Escobar (multiple pterygium) syndrome is progressive and a very rare syndrome. It is generally characterized by multiple pterygia that are found in the cervical, antecubital and popliteal regions. In this report, we present the treatment management of a 14-year-old case with late stage Escobar syndrome who was admitted due to multiple pterygia and bilateral knee contractures. The treatment of thi…
  • Clinical study of histologically proven conjunctival cysts. [Journal Article]
    Saudi J Ophthalmol. 2015 Apr-Jun; 29(2):109-15.Thatte S, Jain J, … Vishnoi A
  • CONCLUSIONS: Careful and intact removal of conjunctival cyst is important to prevent recurrence. Minor modifications in surgical technique according to the size, site and nature of cyst help in intact removal and prevent recurrence.
  • Serum deprivation can suppress receptor-mediated calcium signaling in pterygial-derived fibroblasts. [Journal Article]
    Invest Ophthalmol Vis Sci. 2013 Jul 10; 54(7):4563-70.Fang C, Illingworth CD, … Wormstone IM
  • CONCLUSIONS: Receptor-induced calcium signaling activity is suppressed in pterygial-derived fibroblasts in response to serum deprivation. This correlates with reduced growth rates and a depleted endoplasmic reticulum calcium store. The store plays a key role in cell growth and migration of pterygial-derived fibroblasts. Therefore, the strategic reduction of the vascular network in pterygium will affect the calcium store level and in turn affect functional responses associated with pterygia.
  • Comparative study of pterygium surgery. [Randomized Controlled Trial]
    Prilozi. 2011; 32(2):273-87.Celeva Markovska V, Stankovic Babic G, Zdravkovska Jankuloska M
  • CONCLUSIONS: A comparison of the groups demonstrated that the recurrence rate was highest in the group without transplantation, using only complete suture of the conjunctiva. The excision of the pterygium with conjunctival auto-graft transplantation from the inferior or superior temporal bulbar conjunctiva are highly efficient in terms of low recurrence rates. The modified surgical technique using the graft from the inferior temporal bulbar conjunctivae is preferred because the superior bulbar conjunctiva is intact for eventual future surgical intervention.
  • Progressive keratolysis with pseudopterygium associated with erythema elevatum diutinum. [Case Reports]
    Ophthalmology. 2011 May; 118(5):927-33.Lekhanont K, Patarakittam T, … Vongthongsri A
  • CONCLUSIONS: Erythema elevatum diutinum is a rare, chronic, and recurrent disease that has both dermatologic and ocular manifestations. Peripheral ulcerative keratitis seems to be the most common ocular finding and may be the initial presenting feature of EED. Ophthalmologists should be aware of this rare entity in the differential diagnosis of ulcerative or nonulcerative peripheral keratitis.
  • Unilateral tilted disc and ipsilateral keratoconus in the same eye. [Case Reports]
    BMJ Case Rep. 2011 Jun 17; 2011Ciftci S
  • The objective of this case was to report unilateral tilted disc in a boy with ipsilateral keratoconus. The tilted disc syndrome is a non-hereditary bilateral condition. This configuration is accompanied by situs inversus of the retinal vessels, congenital inferonasal conus, thinning of the inferonasal retinal pigment epithelium and choroid, and myopic astigmatism. Unilateral tilted disc syndrome …
  • [Pterygiun in a tropical region. Analysis of 344 cases in Cameroon]. [Journal Article]
    Bull Soc Belge Ophtalmol. 2009Moukoury Nyolo E, Epee E, … Noa Noa Tina B
  • CONCLUSIONS: The treatment of pterygion should be adapted to individual cases. A long-term follow-up of surgical cases is advised. We recommend that the public could be informed on this pathology through the media and suggest that this study would be initiated in the sahelian region of the country in the future.
  • Diffuse keratoconjunctival proliferation: a novel clinical manifestation. [Journal Article]
    Arch Ophthalmol. 2008 Sep; 126(9):1226-32.Said DG, Mathew M, … Dua HS
  • CONCLUSIONS: The lesions appear to be a clinical variant of classic pterygium with the corneal encroachment being wider, irregular, and more extensive. Histologically, a noninflammatory nonelastotic collagenous accumulation appears to be a predominant feature unlike in classic pterygium where elastotic degeneration is the predominant feature.
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