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(pseudopuberty precocious)
121 results
  • An intriguing case of precocious puberty due to an ovarian mass in an infant. [Journal Article]
    Pediatr Endocrinol Diabetes Metab 2019; 25(2):90-94Dayal D, Seetharaman K, … Srinivasan R
  • We present a rare occurrence of precocious puberty (PP) probably due to an autonomous ovarian cyst in a 15-month-old girl who presented to us with growth spurt, breast and pubic hair development, and vaginal bleeding over the last few months. The clinical presentation was suggestive of central precocious puberty (CPP). However, the rapid progression of pubertal changes and occurrence of menarche …
  • Atypical presentation of Leydig cell tumour in three prepubertal patients: diagnosis, treatment and outcomes. [Case Reports]
    J Pediatr Endocrinol Metab 2019; 32(4):369-374García González M, Casal-Beloy I, … Dargallo Carbonell T
  • Background Testicular tumours are uncommon in children, accounting for only 1% of all childhood tumours. Prepubertal Leydig cell tumours actively secrete testosterone and as a result, patients typically present with isosexual precocious pseudopuberty, this being the first cause of consultation. We present three cases of Leydig cell tumours in prepubertal patients with an atypical presentation. Me…
  • Rare virilizing granulosa cell tumor in an adolescent. [Journal Article]
    Mol Clin Oncol 2017; 6(1):88-90Bús D, Buzogány M, … Vajda G
  • Hormone-producing malignancies are rare in children or adolescent patients: Only 0.1% of all ovarian tumors and 4-5% of granulosa cell tumors occur in the sexually non-active ages. Granulosa cell tumors (GCTs) are sex cord-stromal tumors of the ovary, representing 7-8% of all ovarian neoplasms. A total of 95% of all GCTs are adult-type, and only 5% are diagnosed as juvenile-type GCT. A majority o…
  • Atypical Leydig Cell Tumor in Children: Report of 2 Cases. [Case Reports]
    Pediatrics 2016; 138(5)Mameli C, Selvaggio G, … Zuccotti GV
  • Leydig cell tumors (LCTs) are rare cord-stromal tumors that may occur in testis or ovaries and may produce androgens or estrogens. The majority has been found in men between the ages of 20 and 60 years. Adults with androgen-secreting LCTs are usually asymptomatic; feminizing syndromes may result from the production of estradiol or the peripheral aromatization of testosterone. In children, LCTs us…
  • A case of gradually manifesting McCune-Albright syndrome with a 10-year follow-up. [Journal Article]
    Reprod Med Biol 2016; 15(4):261-265Honda T, Itoh F, … Katabuchi H
  • McCune-Albright syndrome (MAS) is characterized by fibrous dysplasia (FD) of bone, café-au-lait skin pigmentation, and precocious puberty. Here we report a case of a 12-year-old girl with MAS presenting sexual precocity as initial signs, followed by FD of bone with her growth. She was referred to our hospital because of breast budding and abnormal genital bleeding at the age of 2.8 years. On phys…
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