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1,199 results
  • Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety. [Journal Article]
    Psychiatr Danub 2019; 31(Suppl 3):585-590Szarmach J, Cubała WJ, … Wiglusz MS
  • Ketamine is an anaesthetic and analgesic agent that demonstrates the antidepressive effect in major depression. Several administrations routes, dosing schemas and esketamine are investigated in basic and clinical research with particular focus on treatment-resistant depression (TRD) where drug demonstrates its efficacy where very limited alternatives are available. The majority of ketamine studie…
  • Cannabidiol (CBD) use in psychiatric disorders: A systematic review. [Review]
    Neurotoxicology 2019; 74:282-298Bonaccorso S, Ricciardi A, … Schifano F
  • Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different activity compared with the psychotomimetic THC. Most typically, CBD is reported to be used in some medical conditions, including chronic pain. Conversely, the main aim of this systematic review is to assess and summarise the available …
  • The Modulation of Gamma Oscillations by Methamphetamine in Rat Hippocampal Slices. [Journal Article]
    Front Cell Neurosci 2019; 13:277Li Y, Xie X, … Lu C
  • Gamma frequency oscillations (γ, 30-100 Hz) have been suggested to underlie various cognitive and motor functions. The psychotomimetic drug methamphetamine (MA) enhances brain γ oscillations associated with changes in psychomotor state. Little is known about the cellular mechanisms of MA modulation on γ oscillations. We explored the effects of multiple intracellular kinases on MA modulation of γ …
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