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(pulmonary artery wedge pressure)
9,984 results
  • Assessment and Implications of Right Ventricular Afterload in Tetralogy of Fallot. [Journal Article]
    Am J Cardiol 2019Egbe AC, Taggart NW, … Borlaug BA
  • Patients with tetralogy of Fallot (TOF) have abnormal right ventricular (RV) afterload because of residual or recurrent outflow tract obstruction, often with abnormal pulmonary artery (PA) vascular function. The purpose of this study was to determine if RV afterload was independently associated with death and/or heart transplant in patients with TOF. This is a retrospective study of TOF patients …
  • Fibrosis-4 index reflects right-sided filling pressure in patients with heart failure. [Journal Article]
    Heart Vessels 2019Maeda D, Sakane K, … Hoshiga M
  • The fibrosis-4 index (FIB-4 index) is a marker of liver fibrosis. It has been reported that the FIB-4 index in compensated phase is associated with estimated right-sided filling pressure and poor prognosis in patients with heart failure. However, the relationship with invasively obtained right-sided cardiac pressures has been unclear. Hemodynamic status was evaluated by right heart catheterizatio…
  • The neurohormonal basis of pulmonary hypertension in heart failure with preserved ejection fraction. [Journal Article]
    Eur Heart J 2019Obokata M, Kane GC, … Borlaug BA
  • CONCLUSIONS: Subjects with HFpEF display activation of the endothelin and adrenomedullin neurohormonal pathways, the magnitude of which is associated with pulmonary haemodynamic derangements, limitations in RV functional reserve, reduced cardiac output, and more profoundly impaired exercise capacity in HFpEF. Further study is required to evaluate for causal relationships and determine if therapies targeting these counterregulatory pathways can improve outcomes in patients with the HFpEF-PH phenotype.
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