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311 results
  • Effect of age on calcium absorption in postmenopausal women. [Journal Article]
  • AJAm J Clin Nutr 2004; 80(4):998-1002
  • Nordin BE, Need AG, … Horowitz M
  • CONCLUSIONS: A late age-related decrease in calcium absorption is seen in postmenopausal women in addition to the decline that occurs at menopause. This decrease could be due to a decline in either the active calcium transport or diffusion component of the calcium absorption system.
  • A longitudinal study of bone-related biochemical changes at the menopause. [Journal Article]
  • CEClin Endocrinol (Oxf) 2004; 61(1):123-30
  • Nordin BE, WIshart JM, … Horowitz M
  • CONCLUSIONS: We conclude that the menopausal rise in calculated serum ionized calcium without fall in PTH, indicates a change in PTH set-point, and that the falls in gastrointestinal absorption and renal tubular reabsorption of calcium reflect the loss of an oestrogen action at these two sites. Although these changes are sufficient to explain the rise in calcium requirement at the menopause, the association of high bone resorption with normal serum PTH suggests also an increased sensitivity of bone to the action of parathyroid hormone. There is significant 'tracking' of many variables across the menopause despite very significant changes in their absolute values.
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