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4,150 results
  • The Role of Adipokines in Breast Cancer: Current Evidence and Perspectives. [Review]
    Curr Obes Rep 2019Christodoulatos GS, Spyrou N, … Dalamaga M
  • The current review shows evidence for the role of adipokines in breast cancer (BC) pathogenesis summarizing the mechanisms underlying the association between adipokines and breast malignancy. Special emphasis is given also on intriguing insights into the relationship between obesity and BC as well as on the role of novel adipokines in BC development.
  • Extensive serum biomarker analysis in patients with non-small-cell lung carcinoma. [Journal Article]
    Cytokine 2019; 126:154868Cai D, Xu Y, … Duan C
  • Lung cancer is a common malignant disease, nearly 2.09 million new patients occurred last year. Approximately 85% of the patients are classified as non-small-cell lung cancer (NSCLC). It is therefore important to identify new diagnostic and prognostic biomarkers for the early detection of this disease. The presented study identifies biomarkers in the serum of NSCLC patients. The expression of 274…
  • Assessment of selected adipocytokines in obese women with postmenopausal osteoporosis. [Journal Article]
    Endokrynol Pol 2019Głogowska-Szeląg J, Kos-Kudła B, … Siemińska L
  • CONCLUSIONS: Higher leptin concentration and a positive correlation with BMI was confirmed in obese postmenopausal women with osteoporosis. It was also demonstrated that BMD increases with growing BMI. No effect of obesity on the secretion of adiponectin or resistin in women with postmenopausal osteoporosis was found. From among the investigated adipocytokines, only leptin can be considered a bone tissue protective factor in postmenopausal women.
  • The clinical significance of serum adipocytokines level in patients with lung cancer. [Journal Article]
    J Thorac Dis 2019; 11(8):3547-3555Li F, Cao Y, … Chen C
  • CONCLUSIONS: These results suggest that cytokines IGFBP-1, TNF RI, VEGF, TNF RII, PAI-1 and IL-6 may be involved in the development and progression of lung cancer, and TNF RI may be involved in distant metastasis of lung cancer. Additionally, IGFBP-1, TNF RI, VEGF and TNF RII probably represent potentially useful biomarkers for the diagnosis of lung cancer.
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