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256,968 results
  • Cellular localization of cytochrome bd in cyanobacteria using genetic code expansion. [Journal Article]
    Biotechnol Bioeng 2019Friedman M, Ozer E, … Alfonta L
  • Photosynthesis is one of the most fundamental and complex mechanisms in nature. It is a well-studied process, however, some photosynthetic mechanisms are yet to be deciphered. One of the many proteins that take part in photosynthesis, cytochrome bd, is a terminal oxidase protein that plays a role both in photosynthesis and respiration in various organisms, specifically, in cyanobacteria. In order…
  • Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity. [Journal Article]
    Front Neurosci 2019; 13:1027Krasil'nikova I, Surin A, … Pinelis V
  • Glutamate excitotoxicity is implicated in the pathogenesis of numerous diseases, such as stroke, traumatic brain injury, and Alzheimer's disease, for which insulin resistance is a concomitant condition, and intranasal insulin treatment is believed to be a promising therapy. Excitotoxicity is initiated primarily by the sustained stimulation of ionotropic glutamate receptors and leads to a rise in …
  • Single nucleotide mapping of trait space reveals Pareto fronts that constrain adaptation. [Journal Article]
    Nat Ecol Evol 2019Li Y, Petrov DA, Sherlock G
  • Trade-offs constrain the improvement of performance of multiple traits simultaneously. Such trade-offs define Pareto fronts, which represent a set of optimal individuals that cannot be improved in any one trait without reducing performance in another. Surprisingly, experimental evolution often yields genotypes with improved performance in all measured traits, perhaps indicating an absence of trad…
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