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Unbound Medicine.
(respiratory system)
881,276 results
  • Universal SARS-Cov-2 Screening in Women Admitted for Delivery in a Large Managed Care Organization. [Journal Article]
    Am J Perinatol. 2020 Jul 03 [Online ahead of print]Fassett MJ, Lurvey LD, … Getahun D
  • CONCLUSIONS:  The findings suggest that in pregnant women admitted for delivery between April 6 and May 11, 2020 in this large integrated health care system in Southern California, prevalence of SARS-CoV-2 test positive was very low and all patients were asymptomatic on admission.· The prevalence of SARS-CoV-2 infection in a large diverse cohort of term pregnant women was 0.43%.. · 99% of women accepted SARS-CoV-2 screening on admission to labor and delivery.. · All women with positive test results were asymptomatic at the time of testing..
  • Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection. [Journal Article]
    Cell Syst. 2020 Jun 02 [Online ahead of print]Messner CB, Demichev V, … Ralser M
  • The COVID-19 pandemic is an unprecedented global challenge, and point-of-care diagnostic classifiers are urgently required. Here, we present a platform for ultra-high-throughput serum and plasma proteomics that builds on ISO13485 standardization to facilitate simple implementation in regulated clinical laboratories. Our low-cost workflow handles up to 180 samples per day, enables high precision q…
  • Prevalence and Course of Frailty in Survivors of Critical Illness. [Journal Article]
    Crit Care Med. 2020 Jun 26 [Online ahead of print]Brummel NE, Girard TD, … Ely EW
  • CONCLUSIONS: Frailty is common among survivors of critical illness. In the majority, frailty is newly acquired. Roughly one in seven had frailty without co-occurring disability or cognitive impairment. Studies to understand outcomes of frailty that develops as the result of a critical illness and to identify modifiable risk factors for this potentially reversible syndrome are needed.
  • COVID-19 and the Digestive System. [Journal Article]
    Am J Gastroenterol. 2020 Jul; 115(7):1003-1006.Ma C, Cong Y, Zhang H
  • The outbreak of novel coronavirus pneumonia in 2019 (Coronavirus disease 2019 [COVID-19]) is now threatening global public health. Although COVID-19 is principally defined by its respiratory symptoms, it is now clear that the virus can also affect the digestive system. In this review, we elaborate on the close relationship between COVID-19 and the digestive system, focusing on both the clinical f…
  • The Covid-19 pandemic seen from the frontline. [Journal Article]
    Int Braz J Urol. 2020 Jun 05; 46Carmona LEO, Nielfa MDCC, Alvarado ALD
  • COVID-19 disease caused by infection with the SARS-CoV-2 virus produces respiratory symptoms, predominantly of the upper airways, which can progress to pneumonia after 7 days with persistent fever, cough and dyspnea, and even develop a syndrome of acute respiratory distress (ARDS), multi-organ failure and death. Since COVID-19 disease was declared by the WHO there has been a redistribution of the…
  • COVID-19: unravelling the clinical progression of nature's virtually perfect biological weapon. [Review]
    Ann Transl Med. 2020 Jun; 8(11):693.Lippi G, Sanchis-Gomar F, Henry BM
  • Coronavirus disease 2019 (COVID-19) pandemic has shocked the world and caused morbidity and mortality on an unprecedented level in the era of modern medicine. Evidence generated to-date on the virulence and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suggests that COVID-19 may be considered a perfect storm, caused by a nature's virtually perfect biological weapon…
  • Management of Breast Cancer during the COVID-19 Pandemic. [Review]
    Sisli Etfal Hastan Tip Bul. 2020; 54(2):132-135.Citgez B, Yigit B, … Yetkin SG
  • The novel coronavirus disease (COVID-19) arises from the virus SARS-CoV-2 which is similar to the original SARS virus. The most common symptoms of the COVID-19 infection are fever, coughing and shortness of breath. According to the current data, the primary mode of transmission for the COVID-19 virus is between people through respiratory droplets and contact routes. The virus may lead to worse re…
  • Leukostasis in Chronic Lymphocytic Leukemia. [Journal Article]
    Am J Case Rep. 2020 Jul 03; 21:e924798.Singh N, Singh Lubana S, … Sidhu G
  • CONCLUSIONS: Leukostasis, although extremely rare, is a life-threatening complication in patients with CLL. It should be strongly considered in the differential diagnosis of patients with CLL who present with hyperleukocytosis and acute pulmonary symptoms. Clinicians should be aware of this medical emergency, as delayed treatment can increase morbidity and mortality.
  • Intraluminal Carotid Artery Thrombus in COVID-19: Another Danger of Cytokine Storm? [Journal Article]
    AJNR Am J Neuroradiol. 2020 Jul 02 [Online ahead of print]Mohamud AY, Griffith B, … Marin H
  • Coronavirus disease 2019 (COVID-19) is associated with a severe inflammatory response. Inflammation affects atherosclerotic plaque vulnerability and promotes a thrombogenic environment. We report a series of 6 patients with COVID-19 with acute ischemic stroke due to intraluminal carotid artery thrombus presenting during an 8-day period. Six patients were included (5 men) with a mean age of 65.8 y…
  • Initial Stroke Thrombectomy Experience in New York City during the COVID-19 Pandemic. [Journal Article]
    AJNR Am J Neuroradiol. 2020 Jul 02 [Online ahead of print]Yaeger KA, Fifi JT, … Mocco J
  • New York City has become the global epicenter of the coronavirus 2019 (COVID-19) pandemic. Despite a massive shift in health care resources, cerebrovascular disease continues to be a substantial burden. We review the first 10 patients undergoing thrombectomy following a series of governmental and institutional policy changes diverting resources to the care of critically ill patients with COVID-19…
  • Neurologic alterations in an HIV adult patient with pertussis: a case report. [Journal Article]
    BMC Infect Dis. 2020 Jul 02; 20(1):471.Arango-Granados MC, Trompa IM
  • CONCLUSIONS: This case illustrates the biological plausibility of neurologic complications of pertussis in adults, which, albeit rare, can cause important morbidities. Future research should explore whether there are differences in the clinical presentation, risk factors and pathophysiology of the disease among adults or interventions aimed at preventing or treating pertussis encephalopathy.
  • Clinical Implications of SARS-CoV-2 Infection in the Viable Preterm Period. [Journal Article]
    Am J Perinatol. 2020 Jul 02 [Online ahead of print]Gulersen M, Blitz MJ, … Bornstein E
  • CONCLUSIONS:  The likelihood of PTB during hospitalization with SARS-CoV-2 infection is significantly lower among women diagnosed in the early preterm period compared with late preterm. Most women with SARS-CoV-2 infection in the early preterm period recovered and were discharged home. The majority of PTB were indicated and not due to spontaneous preterm labor.· Preterm delivery is less likely among women diagnosed in the early preterm compared with late preterm.. · Most women infected in the early preterm period recovered and were discharged home undelivered.. · The majority of preterm birth were indicated and not due to spontaneous preterm labor..
  • A case of possible atypical demyelinating event of the central nervous system following COVID-19. [Case Reports]
    Mult Scler Relat Disord. 2020 Jun 24; 44:102324.Zoghi A, Ramezani M, … Sahraian MA
  • After the novel coronavirus disease outbreak first began in Wuhan, China, in December 2019, the viral epidemic has quickly spread across the world, and it is now a major public health concern. Here we present a 21-year-old male with encephalomyelitis following intermittent vomiting and malaise for 4 days. He reported upper respiratory signs and symptoms 2 weeks before this presentation. Two cereb…
  • PROPHETIC: Prospective Identification of Pneumonia in Hospitalized Patients in the Intensive Care Unit. [Journal Article]
    Chest. 2020 Jun 29 [Online ahead of print]Bergin SP, Coles A, … Holland TL
  • CONCLUSIONS: Treatment for nosocomial pneumonia is common among intensive care unit patients receiving high levels of respiratory support, yet more than half of patients treated do not fulfill standard diagnostic criteria for pneumonia. Application of simple clinical criteria may improve the feasibility of clinical trials of pneumonia prevention and treatment by facilitating prospective identification of patients at highest risk.
  • Histopathologic Assessment of Suspected Idiopathic Pulmonary Fibrosis: Where We Are and Where We Need to Go. [Journal Article]
    Arch Pathol Lab Med. 2020 Jul 02 [Online ahead of print]Smith ML, Hariri LP, … Beasley MB
  • CONCLUSIONS: Both guidelines provide pathologists with a tool to relay to the clinician the likelihood that a biopsy represents UIP, and serve as an adjunct, not a replacement, for traditional histologic diagnosis. There are multiple challenges with implementing the guidelines, including (1) lack of clarity on the quantity and quality of histologic findings required, (2) lack of recognition that histologic features cannot be assessed independently, and (3) lack of guidance on how pathologists should incorporate clinical and radiographic information. Current criteria for "probable UIP" and "indeterminate for UIP" hinder accurate reflection of the likelihood of IPF. These challenges highlight the need for further morphologic-based investigations in the field of pulmonary pathology.
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