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5,773 results
  • Mood, anxiety and olfactory dysfunction in COVID-19: evidence of central nervous system involvement? [Journal Article]
    Laryngoscope. 2020 Jul 02 [Online ahead of print]Speth MM, Singer-Cornelius T, … Sedaghat AR
  • CONCLUSIONS: Despite the occurrence of symptoms-such as SOB-associated with severe manifestations of COVID-19, only the severities of smell and taste loss were associated with depressed mood and anxiety. These results may raise the novel possibility of emotional disturbance as a CNS manifestation of COVID-19 given trans-olfactory tract penetration of the central nervous system (CNS) by coronaviruses.
  • ENT manifestation in COVID-19 patients. [Journal Article]
    Auris Nasus Larynx. 2020 Jun 15 [Online ahead of print]El-Anwar MW, Elzayat S, Fouad YA
  • CONCLUSIONS: ENT manifestations for COVID-19 are not common as fever and cough. But, a universal questionnaire using well-defined COVID-19 manifestations is needed to make the COVID-19 data precisely defined, complete and homogenous.
  • Olfactory and taste disorders in COVID-19: a systematic review. [Review]
    Braz J Otorhinolaryngol. 2020 Jun 09 [Online ahead of print]Costa KVTD, Carnaúba ATL, … Menezes PL
  • CONCLUSIONS: Olfactory/gustatory disorders may occur at varying intensities and prior to the general symptoms of COVID-19 and should be considered as part of the clinical features of COVID-19, even in mild cases. There is still no scientific evidence of specific treatments for such disorders in COVID-19 disease.
  • Spontaneous Skull Base Cerebrospinal Fluid Leaks and Their Relationship to Idiopathic Intracranial Hypertension. [Journal Article]
    Am J Rhinol Allergy. 2020 Jun 19 [Online ahead of print]Bidot S, Levy JM, … Biousse V
  • CONCLUSIONS: Striking demographic overlap exists between IIH patients and those with spontaneous CSF leak. Definite IIH was present in approximately 20% of our patients. However, its true prevalence is likely higher than identified by using classic criteria. We therefore hypothesize that an active CSF leak serves as an auto-diversion for CSF, thereby "treating" the intracranial hypertension and eliminating characteristic signs and symptoms at initial presentation.
  • Identification of Symptoms Prognostic of COVID-19 Severity: Multivariate Data Analysis of a Case Series in Henan Province. [Journal Article]
    J Med Internet Res. 2020 06 30; 22(6):e19636.Li J, Chen Z, … Dai X
  • CONCLUSIONS: Fatigue and expectoration are signs of severe COVID-19 infection. Shortness of breath, chest distress, muscle or joint ache, and dry cough are prevalent in severe patients. Expectoration is commonly present in older individuals and patients with cardiovascular disorders, including hypertension. Shortness of breath is prognostic of severe infection in male patients. Stuffed nose and nausea are favorable prognostic factors of severe infection, especially among male patients.
  • Pediatric COVID-19: Systematic review of the literature. [Journal Article]
    Am J Otolaryngol. 2020 Jun 06; 41(5):102573.Patel NA
  • CONCLUSIONS: In contrast to adults, most infected children appear to have a milder course and have better outcomes overall. Additional care may be needed for children with comorbidities and younger children. This review also suggests that unilateral CT chest imaging findings were seen in 36.4% pediatric COVID-19 patients. This is particularly concerning as the work-up of pediatric patients with cough may warrant a bronchoscopy to evaluate for airway foreign bodies. Extra precautions need to be taken with personal protective equipment for these cases, as aerosolizing procedures may be a method of viral transmission.
  • Enlargement of Dorello's Canal as a Novel Radiographic Marker of Idiopathic Intracranial Hypertension. [Journal Article]
    J Neurol Surg B Skull Base. 2020 Jun; 81(3):232-236.Eggerstedt M, Dua SG, … Tajudeen BA
  • Objectives  The objective of this study is to compare the visibility and size of Dorello's canal (DC) on magnetic resonance imaging between patients with idiopathic intracranial hypertension (IIH) and control patients, for its evaluation as a potential novel marker for chronic increased intracranial pressure (ICP). Design  Retrospective blinded case-control study. Setting  Tertiary care academic …
  • Neonates Hospitalized with Community-Acquired SARS-CoV-2 in a Colorado Neonatal Intensive Care Unit. [News]
    Neonatology. 2020 Jun 04 [Online ahead of print]White A, Mukherjee P, … Dietz RM
  • CONCLUSIONS: Infants with community-acquired SARS-CoV-2 may require hospitalization due to rule-out sepsis guidelines if found to have fever and/or hypoxia. Caregivers of neonates should exercise recommended guidelines before contact with neonates to limit community spread of SARS-CoV-2 to this potentially vulnerable population, including isolation, particularly as asymptomatic cases become prevalent.
  • Leukocytoclastic Vasculitis: An Early Skin Biopsy Makes a Difference. [Case Reports]
    Cureus. 2020 May 01; 12(5):e7912.Chango Azanza JJ, Calle Sarmiento PM, … Modi V
  • Leukocytoclastic vasculitis (LCV) is an uncommon condition with a broad differential diagnosis. Although the clinical history, physical examination, and laboratory workup are pivotal when formulating a differential diagnosis of LCV, a skin biopsy is required in most cases to elucidate the cause. The diagnostic yield of a skin biopsy increases within the first 24 to 48 hours of the lesion onset in…
  • Nasoseptal Flap Necrosis After Endoscopic Skull Base Surgery in the Setting of SARS-CoV-2/COVID-19. [Case Reports]
    World Neurosurg. 2020 May 29 [Online ahead of print]Talmor G, Grube JG, … Hsueh WD
  • CONCLUSIONS: To our knowledge, this is the first reported case of NSF necrosis in a patient with COVID-19. We postulate that the thrombotic complications of COVID-19 may have contributed to vascular pedicle thrombosis and NSF necrosis. Although the pathophysiology of SARS-CoV-2 and its effect on the nasal tissues is still being elucidated, this case highlights some challenges of performing endoscopic skull base surgery in the era of COVID-19.
  • [A case of acute pneumonia with prolonged false-positive results using an influenza test kit]. [Journal Article]
    Nihon Ronen Igakkai Zasshi. 2020; 57(2):195-199.Kikuchi M, Fujita S, Senoo K
  • Influenza (flu) is a prominent infectious disease that worsens the general prognosis of older adults. We herein report a case of a clinically odd and rare reaction on an instant diagnostic kit for influenza. An 81-year-old man with a fever and rhinorrhea consulted our hospital. He had a history of dementia of Alzheimer's type and rheumatoid arthritis and had been treated with oral prednisolone (1…
  • Chronic cough related to the upper airway cough syndrome: one entity but not always the same. [Journal Article]
    Eur Arch Otorhinolaryngol. 2020 May 27 [Online ahead of print]Dąbrowska M, Arcimowicz M, … Krenke R
  • CONCLUSIONS: NAR is the most common upper airway disease associated with UACS. Clinical characteristics of UACS patients with AR and NAR are similar with only minor differences between these groups. It seems reasonable to plan further studies concerning relationship of NAR and cough sensitivity, also in terms of potential similar neurogenic mechanism.
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