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1,614 results
  • Pharmacological profile of vascular activity of human stem villous arteries. [Journal Article]
    Placenta 2019; 88:12-19Sander KN, Ali TY, … Khan RN
  • CONCLUSIONS: Stem villous arteries behave differently to vessels of the systemic vasculature and results indicate that the placenta is cut off from the systemic maternal vascular regulation. Particularly, endothelium-dependent processes were attenuated in the placental vasculature, creating a need to determine the role of the endothelium in the placenta in future studies.
  • The critical role of persistent sodium current in hippocampal gamma oscillations. [Journal Article]
    Neuropharmacology 2019; :107787Kang YJ, Clement EM, … Lee SH
  • Gamma network oscillations in the brain are fast rhythmic network oscillations in the gamma frequency range (∼30-100 Hz), playing key roles in the hippocampus for learning, memory, and spatial processing. There is evidence indicating that GABAergic interneurons, including parvalbumin-expressing basket cells (PVBCs), contribute to cortical gamma oscillations through synaptic interactions with exci…
  • Stage-specific riluzole effect in amyotrophic lateral sclerosis: a retrospective study. [Journal Article]
    Amyotroph Lateral Scler Frontotemporal Degener 2019; :1-4Thakore NJ, Lapin BR, … Pooled Resource Open-Access Als Clinical Trials Consortium
  • CONCLUSIONS: This examination of cohorts closely followed in clinical trials finds a beneficial effect of riluzole that is predominantly but not exclusively in later stages of ALS. This analytic framework has utility to discern stage-specific treatment effects, and for refined health economic analyses.
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