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681 results
  • Entry of betaherpesviruses. [Journal Article]
    Adv Virus Res 2019; 104:283-312Nishimura M, Mori Y
  • In this chapter, we present an overview on betaherpesvirus entry, with a focus on human cytomegalovirus, human herpesvirus 6A and human herpesvirus 6B. Human cytomegalovirus (HCMV) is a complex human pathogen with a genome of 235kb encoding more than 200 genes. It infects a broad range of cell types by switching its viral ligand on the virion, using the trimer gH/gL/gO for infection of fibroblast…
  • Erratum. [Journal Article]
    J Child Health Care 2019; :1367493519864764
  • Phonpruk K, Flowers, K, Naughton G, et al. (2019). Analysis of written resources for parents of children discharged from a paediatric emergency department. Journal of Child Health Care. Epub ahead of print 3 June 2019. DOI: 10.1177/1367493519852460 In this article, the layout of Table 2 was not wholly correct. The revised table with the correct layout is given below. All the subsequent versions o…
  • Clinical Characteristics of Primary HHV-6B Infection in Children Visiting the Emergency Room. [Journal Article]
    Pediatr Infect Dis J 2019; 38(10):e248-e253Hattori F, Kawamura Y, … Yoshikawa T
  • CONCLUSIONS: Primary HHV-6B infection accounted for 12% of ER visits. Secondary febrile seizures, in particular the complex type, were considered to be a major contributor to the disease burden of primary HHV-6B infection. The timing of primary HHV-6B infection occurred at older ages than in past reports, and the frequency of inapparent infection was higher in older patients.
  • StatPearls: Herpes Virus Type 6 [BOOK]
    StatPearls Publishing: Treasure Island (FL) King Orinthia O Wyckoff Heights Medical Center Al Khalili Yasir Y Virginia Commonwealth University BOOK
  • Human herpesvirus 6 (HHV-6) was initially discovered in blood lymphocytes of adults with lymphoproliferative diseases or AIDS and was labeled human B-lymphotropic virus.  Further research identified HHV-6 in CD4+ lymphocytes and as a member of the herpesviruses.  As it was the sixth herpesvirus isolated, it was then subsequently renamed human herpesvirus 6. Typical of a herpes virus, HHV-6 has be…
  • The rash with maculopapules and fever in children. [Review]
    Clin Dermatol 2019 Mar - Apr; 37(2):119-128Muzumdar S, Rothe MJ, Grant-Kels JM
  • Several medical conditions can cause children to present with fever and a maculopapular rash Although some presentations are benign, others may be medical emergencies, which warrant a prompt diagnosis. We review some of the more common causes of fever and maculopapular dermatitirs, rash including infectious processes (roseola; rubeola; rubella; parvovirus B19; hand, foot, and mouth disease; scarl…
  • Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress. [Journal Article]
    J Gen Virol 2019; 100(1):89-98Romeo MA, Masuelli L, … Cirone M
  • Herpesviruses are known to manipulate autophagy to optimize their replication, counteract immune response and probably to promote tumourigenesis. This study explored, for the first time, the impact of human herpesvirus (HHV)-6 lytic infection on autophagy and demonstrated that HHV-6A and B (viruses sharing more than 80 % homology) differently affected this cellular process. Indeed, while HHV-6A (…
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