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(sirolimus)
21,132 results
  • Pathway Interactions Based on Drug-Induced Datasets. [Journal Article]
  • CICancer Inform 2019; 18:1176935119851518
  • Kim S
  • In this study, we identified enrichment pathway connections from MCF7 breast cancer epithelial cells that were treated with 87 drugs. We extracted drug-treated samples, where the sample size was grea…
  • mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV. [Journal Article]
  • CCCell Commun Signal 2019 Jun 14; 17(1):64
  • Yang JY, Madrakhimov SB, … Park TK
  • CONCLUSIONS: Our study suggests the mTOR as a critical player during CNV development in laser-induced mouse model through differentially acting with the mTORC1 and mTORC2. mTORC1 activity was high predominantly in inflammatory cells in CNV lesion, while mTORC2 activity was higher in vascular components and the RPE.
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