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(skeletal system)
35,546 results
  • Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration. [Journal Article]
    Front Physiol 2019; 10:1216Palma A, Perpetuini AC, … Cesareni G
  • Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell-cell interactions and/or paracrine signals, influencing fate decisions via the activation or repression of internal signaling cascades. These are highly dynamic processes, occur…
  • A different background of arrhythmia in siblings with a positive family history of sudden death at young age. [Case Reports]
    Ann Noninvasive Electrocardiol 2019; :e12707Stępień-Wojno M, Franaszczyk M, … Bilińska ZT
  • We present two symptomatic sisters who had a positive family history of sudden death. None of them had structural heart disease. In the 25-year-old proband, complex ventricular arrhythmia, cardiac conduction system disease, and skeletal muscle weakness were found. Genetic examination showed a pathogenic intronic variant in the desmin gene in the proband only. In the elder sister with palpitations…
  • The use of aliskiren as an antifibrotic drug in experimental models: A systematic review. [Journal Article]
    Drug Dev Res 2019Altarejo Marin T, Machado Bertassoli B, … Feder D
  • Aliskiren is an oral antihypertensive medication that acts by directly inhibiting renin. High levels of circulating renin and prorenin activate the pathological signaling pathway of fibrosis. This drug also reduces oxidative stress. Thus, the aim of this systematic review is to analyze experimental studies that show the actions of aliskiren on fibrosis. PubMed and LILACS databases were consulted …
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