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90,539 results
  • Kinase-Inhibitory Nucleoside Derivatives from the Pacific Bryozoan Nelliella nelliiformis. [Journal Article]
    J Nat Prod 2020Bracegirdle J, Gordon DP, … Keyzers RA
  • Marine organisms are a valuable source of bioactive natural products, yet bryozoan invertebrates have been relatively understudied. Herein, we report nelliellosides A and B, new secondary metabolites of the Pacific bryozoan Nelliella nelliiformis, found using NMR-guided isolation. Their structures, including absolute configurations, were elucidated using spectroscopic and chromatographic techniqu…
  • New insights into 99Tc(VII) removal by pyrite: a spectroscopic approach. [Journal Article]
    Environ Sci Technol 2020Rodriguez DM, Mayordomo N, … Stumpf T
  • 99Tc(VII) uptake by synthetic pure pyrite was studied in a wide pH range from 3.5 to 10.5 using batch experiments at 21°C combined with scanning electron microscopy (SEM), X-ray absorption spectroscopy (XAS), X-ray photoelectron spectroscopy (XPS) and Raman microscopy. We found that pyrite removes Tc quantitatively from solution (log Kd = 5.0 ± 0.1) within one day at pH ≥ 5.5. At pH < 5.5 the upt…
  • Four new polyynes from Codonopsis pilosula collected in Yunnan province, China. [Journal Article]
    Nat Prod Res 2020; :1-8Su JS, Qin FY, … Zhang Y
  • Choushenpilosulynes D-G (1-4): four new polyynes were isolated from the roots of Codonopsis pilosula (Campanulaceae) cultivated in Yunnan province, China. Their structures were identified by spectroscopic methods. Bioactive evaluation showed that choushenpilosulynes E (2) and F (3) demonstrated potent inhibitory effect on lipid formation induced by 100 μM oleic acid stimulation. In addition, chou…
  • A new phenol derivative isolated from mangrove-derived fungus Eupenicillium sp. HJ002. [Journal Article]
    Nat Prod Res 2020; :1-7Mei RQ, Nong XH, … Chen GY
  • A new phenol derivative, 3-chloro-5-hydroxy-4-methoxyphenylacetic acid methyl ester (1), along with five known compounds methyl 4-hydroxyphenylacetate (2), cytosporone B (3), (R)-striatisporolide A (4), (R)-butanedioic acid (5) and ergosterol (6) were isolated from the mangrove-derived fungus Eupenicillium sp. HJ002. Their structures were established by spectroscopic methods, GIAO based 13C NMR c…
  • Anti-inflammatory isocoumarins from the bark of Fraxinus chinensis subsp. rhynchophylla. [Journal Article]
    Nat Prod Res 2020; :1-8Lee BZ, Kim CS, … Hong K
  • A new isocoumarin (1) named fraxicoumarin was isolated from the bark of Fraxinus chinensis subsp. rhynchophylla along with three known compounds (2-4). The structure of the new compound was established by extensive spectroscopic studies and chemical evidence. The anti-inflammatory effects of the isolated compounds (1-4) on lipopolysaccharide (LPS)-induced RAW 264.7 macrophage cells were evaluated…
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