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1,313 results
  • Effects of 5-hydroxytryptamine on spermatozoal hyperactivation and in vitro fertilization in mice. [Journal Article]
    J Reprod Dev 2019Sugiyama Y, Fujinoki M, Shibahara H
  • In this study, we examined the effects of 5-hydroxytryptamine (5-HT) on the motility and hyperactivation of mouse spermatozoa. In addition, we examined whether 5-HT increases the success of in vitro fertilization (IVF) in mice. Interestingly, 5-HT and agonists of the 5-HT2, 5-HT3, 5-HT4, and 5-HT7 receptors significantly increased the percentage of hyperactivated spermatozoa but did not affect th…
  • Immune regulatory molecules as modifiers of semen and fertility: A review. [Review]
    Mol Reprod Dev 2019Archana SS, Selvaraju S, … Krawetz SA
  • Declining fertility rates in both human and animals is a cause for concern. While many of the infertility cases are due to known causes, idiopathic infertility is reported in 30% of the infertile couples. In such cases, 18% of the infertile males carry antisperm antibodies (ASAs). Such data are lacking in livestock, wherein 20-30% of the animals are being culled due to low fertility. In males, th…
  • Heat induced differential pattern of DNA fragmentation in male germ cells of rats. [Journal Article]
    J Therm Biol 2019; 84:351-356Kaushik K, Kaushal N, … Kalla NR
  • Spermatogenesis being a highly dynamic processes is highly vulnerable to various stresses including heat stress. Though, the relationship between physiological temperature and male germ cells is certainly immense, the magnitude of spermatozoal damage after exposure to heat is evidently degree and dose dependent. Further, there are contradictory reports related to germ cells apoptosis in relation …
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