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19,844 results
  • Common variable immune deficiency: case studies. [Journal Article]
    Blood 2019; 134(21):1787-1795Cunningham-Rundles C
  • Common variable immune deficiency (CVID) is one of the most common congenital immune defects encountered in clinical practice. The condition occurs equally in males and females, and most commonly in the 20- to 40-year-old age group. The diagnosis is made by documenting reduced serum concentrations of immunoglobulin G (IgG), IgA, and usually IgM, together with loss of protective antibodies. The ge…
  • Cementless bipolar hemiarthroplasty in a patient with PMF: a case report. [Case Reports]
    J Surg Case Rep 2019; 2019(11):rjz274Alturki AA, Alshammari NA, … Alhandi AA
  • Myelofibrosis is a myeloproliferative disease that falls under a group of bone marrow malignancies known as myeloproliferative neoplasms. It manifests with splenomegaly, anemia, leukocytosis and, less commonly, bone pain. Ruxolitinib, Janus kinase inhibitor, has been shown to increase survival, to improve symptoms and has the potential to decrease osteosclerotic changes. Herein, we present a case…
  • [A Case of POEMS Syndrome Treated by Ld Prior to HDCTx Followed by aPBSCT]. [Journal Article]
    Gan To Kagaku Ryoho 2019; 46(11):1799-1802Fujii T, Ohno N, … Matsunaga T
  • A man in his late 40s was presented to a hospital with complaints of peripheral numbness and fatigue. Systemic edema, pleural effusion and ascites, pigmentation, splenomegaly, and CT findings of osteoplastic changes suggested POEMS syndrome. He was referred to our division, and a bone marrow examination indicated MGUS. However, his serum level of vascular endothelial growth factor(VEGF)was elevat…
  • Multiple Neurologic Deficits and Cognitive Decline in a Young Woman. [Journal Article]
    Ann Indian Acad Neurol 2019 Oct-Dec; 22(4):506-512Elavarasi A, George J, … Goyal V
  • We present the clinicopathologic conference of a 34-year-old lady with history of facial palsy 14 years ago who developed new deficits of mononeuritis multiplex, maculopapular rash, pancytopenia, splenomegaly, lung involvement and cognitive decline rapidly over three years. Investigations revealed pancytopenia, reversal of albumin globulin ratio, mediastinal adenopathy, ANA positivity, low C3 lev…
  • Cavernous Transformation of Portal Vein in the Setting of Protein C and Anti-thrombin III Deficiency. [Case Reports]
    Cureus 2019; 11(9):e5779Nasim M, Majid B, … Irfan I
  • Cavernous transformation of the portal vein (CTPV), also known as portal cavernoma, is a sequelae of thrombosis in the portal vein causing its occlusion and portal hypertension. The etiology, however, remains unknown. Gastroesophageal variceal bleeding, splenomegaly, portosystemic collaterals, and ultimate hematologic abnormalities are among the prominent clinical features. Among the causes, pred…
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