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25,090 results
  • A Rare Presentation of Epstein-Barr Virus Infection. [Journal Article]
    J Emerg Med 2020Teijido J, Tillotson K, Liu JM
  • Epstein-Barr virus (EBV) is a herpesvirus spread by intimate contact. It is known to cause infectious mononucleosis. Complications, including hematologic pathology and splenic rupture, are uncommon. This report is a case of EBV-induced autoimmune hemolytic anemia and biliary stasis.
  • Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells. [Journal Article]
    Nat Immunol 2020Hayward SL, Scharer CD, … Kohlmeier JE
  • Tissue-resident memory T cells (TRM cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In the present study, we found that the airway environment drove transcriptional and epigenetic changes that specifically regulated the cytolytic functions of airway TRM cells and promoted apoptosis due to amino acid starvation and activation …
  • Abdominal pain in a patient with sickle cell disease with multiple complications. [Case Reports]
    Turk Pediatri Ars 2019; 54(4):267-271Mehrabani S, Tammadoni A, Osia S
  • Sickle cell disease is an inherited autosomal recessive hemoglobinopathy. Acute abdominal pain is the cause of hospitalization in 10% of patients with sickle cell disease and usually occurs during vaso-occlusion or distal tissue ischemia. Determining the etiology of abdominal pain is very difficult in these patients because it is associated with several rare diagnoses, such as pancreatitis and sp…
  • Pregnancy Status Alters IL-21-mediated Effects on Murine B Lymphocytes. [Journal Article]
    Reproduction 2020Fröhlich C, Ehrhardt J, … Muzzio DO
  • A favorable outcome of pregnancy depends greatly on an adequate balance of immune protection and fetal tolerance at the fetomaternal interface. IL-21 is a pro-inflammatory cytokine associated to altered immune responses in auto-immune diseases. IL-21 has pleiotropic functions, including induction of Th17 T cells, inhibition of Treg development, and modulation antibody responses of B lymphocytes. …
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