Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.
(subacute myelo optic myelo optico neuropathy)
121 results
  • Sleep problems in subacute myelo-optico neuropathy (SMON). [Journal Article]
    J Clin Neurosci. 2019 Oct; 68:128-133.Hishikawa N, Takemoto M, … Abe K
  • Subacute myelo-optico neuropathy (SMON) patients typically suffer from sequelae that cause sleep disturbances. We sought to examine the prevalence of sleep problems among SMON patients. We conducted a questionnaire-based survey concerning sleep problems among 106 SMON patients, and 110 age- and gender-matched control participants. The prevalence of subjective insomnia (6 ≤ Athens Insomnia Scale s…
  • Tongue strength in patients with subacute myelo-optico-neuropathy. [Journal Article]
    J Clin Neurosci. 2018 Jan; 47:84-88.Yamashita S, Nakama T, … Ando Y
  • Subacute myelo-optico-neuropathy (SMON) is a neurodegenerative disease that may be caused by overdose or prolonged oral administration of clioquinol. Recently, dysphagia has attracted attention as a complication of SMON. To investigate lingual control in SMON, we examined patients with SMON using assessments of maximum tongue pressure, compared with dysphagia-related diseases, such as sporadic in…
  • [SMON: toxicity of clioquinol and the status quo]. [Review]
    Brain Nerve. 2015 Jan; 67(1):49-62.Konagaya M
  • Subacute myelo-optico-neuropathy (SMON) is a disease characterized by subacute onset of sensory and motor disorders in the lower half of the body and visual impairment preceded by abdominal symptoms. A large number of SMON were observed throughout Japan, and the total number of cases reached nearly 10,000 by 1970. Despite clinical features mimicking infection or multiple sclerosis, SMON was confi…
  • Superoxide dismutase as a target of clioquinol-induced neurotoxicity. [Journal Article]
    Biochem Biophys Res Commun. 2014 Sep 12; 452(1):181-5.Kawamura K, Kuroda Y, … Mitsui T
  • Subacute myelo-optico-neuropathy (SMON) is a progressive neurological disorder affecting the spinal cord, peripheral nerves and optic nerves. Although it has been assumed that SMON was caused by intoxication of clioquinol, the mechanism underlying clioquinol-induced neurotoxicity is not fully understood. This study aimed to clarify the relevance of oxidative stress to clioquinol-induced neurotoxi…
  • [Spinal anesthesia in a patient with SMON disease]. [Case Reports]
    Masui. 2010 Sep; 59(9):1198-200.Kimoto M, Murao K, … Shingu K
  • We report a patient with subacute myelo-optico-neuropathy (SMON) in whom spinal anesthesia was employed to treat fracture of the femur neck. An 87-year-old woman was diagnosed as having SMON at the age of 45. The patient was admitted to our hospital with fracture of the femur neck. Aspiration pneumonia was also suspected with shadow in the right lung on the chest X-P The percutaneous oxygen satur…
  • Cervical MRI of subacute myelo-optico-neuropathy. [Case Reports]
    Spinal Cord. 2011 Feb; 49(2):182-5.Kimura E, Hirano T, … Uchino M
  • CONCLUSIONS: Although fainter, the abnormal T2 MRI signals we observed were similar to and occurred in the same locations as those reported in copper-deficient myelo-neuropathy patients. We suggest that these findings are useful to study the mechanism of clioquinol toxicity before using it to treat neurodegenerative diseases such as Alzheimer's disease.
  • Clinical studies on rising and re-rising neurological diseases in Japan--a personal contribution. [Review]
    Proc Jpn Acad Ser B Phys Biol Sci. 2010; 86(4):366-77.Igata A
  • Throughout my research life, I experienced to discover the causes of some neurological diseases in Japan. 1) SMON (subacute myelo-optico-neuropathy). Since the early 1960s, a peculiar neurological disease became prevalent throughout Japan. Through the chemical analysis of the green urine, characteristic of this disease, it was found that this disease was caused by intoxication of the administered…
  • [SMON--a model of the iatrogenic disease]. [Review]
    Rinsho Shinkeigaku. 2003 Nov; 43(11):866-9.Takasu T
  • The subacute myelo-optico-neuropathy (SMON) was hazard caused by clioquinol, an antiseptic, prescribed for the treatment of diarrhea and other bowel symptoms. Its overdosing and long-term taking led to the occurrence of SMON, for which physicians should be responsible. Clioquinol, originally a disinfectant powder for external use, was diverted later to a drug for internal use to sterilize the bow…
  • [Anesthetic management of two patients with the history of SMON]. [Journal Article]
    Masui. 2002 Aug; 51(8):907-9.Sato H, Okawa I, … Kumazawa T
  • Patients of subacute myelo-optico-neuropathy (SMON) suffer from neurological disorders for a long time. The authors report anesthetic management of two patients with SMON. One patient was a 82-year-old woman suffering from SMON for 49 years. Sensory examination revealed numbness and hypesthesia in the both lower extremities. She underwent open reduction for femoral neck fracture. The other patien…
  • Subacute myelo-optico-neuropathy: clioquinol intoxication in humans and animals. [Review]
    Neuropathology. 2000 Sep; 20 Suppl:S20-4.Tateishi J
  • It remains a tragic event that some 10,000 individuals in Japan developed a unique neurologic disease, subacute myelo-optico-neuropathy (SMON). Many of the affected patients still suffer serious sequelae, such as dysesthesia and muscle weakness in the lower extremities, and loss or deficits in visual acuity. Neuropathologic studies on SMON patients and experimental reproduction of the disease in …
  • [Spinal anesthesia for a patient with long-term SMON]. [Case Reports]
    Masui. 1999 Jan; 48(1):79-80.Yuasa H, Higashizawa T, … Koga Y
  • SMON (subacute myelo-optico-neuropathy) may result from clioquinol neurotoxicity. An 81-year-old woman underwent internal fixation for left intertrochanteric fracture. She had been diagnosed as having SMON twenty years previously. Sensory examination revealed paresthesia and decreased deep sensation in the lower extremity. A recent neuropathological report shows that in long-term SMON of about fi…
  • CYP2D6 HhaI genotype and the neuroleptic malignant syndrome. [Clinical Trial]
    Neuropsychobiology. 1999; 39(1):33-7.Iwahashi K, Yoshihara E, … Igarashi K
  • To investigate the relationship between CYP2D6 genotypes (reported to be associated with the susceptibilities to Parkinson's disease and multisystem atrophy) and the possible susceptibility to neuroleptic malignant syndrome (NMS) and subacute myelo-optico-neuropathy (SMON), we analyzed the CYP2D6 gene by polymerase chain reaction and restriction fragment length polymorphism in Japanese schizophre…
  • Auditory and colored visual P300 in patients with sequelae of subacute myelo-optico-neuropathy. [Journal Article]
    Electroencephalogr Clin Neurophysiol. 1994 Oct; 91(4):265-74.Ikeda T, Fukushima T, … Kinjo Y
  • To study the cognitive function in 13 patients with sequelae of subacute myelo-optico-neuropathy (SMON), event-related potentials (ERPs) were elicited with tones, clicks, and colored visual stimuli in different tasks. P300 latency was delayed, and P300 amplitude reduced or absent in 5 patients (38%), although neuropsychological assessment for dementia did not differ between patients and 21 age-ma…
New Search Next