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(subpleural)
1,823 results
  • Matrisome Properties of Scaffolds Direct Fibroblasts in Idiopathic Pulmonary Fibrosis. [Journal Article]
    Int J Mol Sci 2019; 20(16)Elowsson Rendin L, Löfdahl A, … Westergren-Thorsson G
  • In idiopathic pulmonary fibrosis (IPF) structural properties of the extracellular matrix (ECM) are altered and influence cellular responses through cell-matrix interactions. Scaffolds (decellularized tissue) derived from subpleural healthy and IPF lungs were examined regarding biomechanical properties and ECM composition of proteins (the matrisome). Scaffolds were repopulated with healthy fibrobl…
  • Trajectory of lung function to pleuroparenchymal fibroelastosis late after haematopoietic stem-cell transplantation. [Case Reports]
    Respir Med Case Rep 2019; 28:100915Barisione G, Dominietto A, … Brusasco V
  • Pleuroparenchymal fibroelastosis is characterized by upper lobes subpleural intra-alveolar fibrosis and elastosis with visceral pleural fibrosis, which may occur after allogenic haematopoietic stem-cell transplantation (HSCT). The longitudinal changes of lung function preceding this complication have not been described. We report the case of an adult woman undergoing allogeneic HSCT for Hodgkin's…
  • Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. [Journal Article]
    Am J Respir Crit Care Med 2019Hobbs BD, Putman RK, … COPDGene Investigators, ECLIPSE Investigators, SPIROMICS Research Group, and UK ILD Consortium
  • Rationale Interstitial lung abnormalities (ILA) are associated with the highest genetic risk locus for IPF; however, the extent to which there is additional overlap with IPF, or unique associations among those with ILA is not known. Objectives To perform a genome-wide association study (GWAS) of ILA. Methods: ILA and the subpleural-predominant subtype were assessed on chest computed tomography (…
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