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264,871 results
  • Why do humans get acne? A hypothesis. [Journal Article]
    Med Hypotheses 2019; 134:109412Shannon JF
  • Acne is a disease unique to humans and is associated with sebaceous glands that are found at high density on the scalp, forehead and face. Despite being a near universal problem in adolescence, the reason why such troublesome sebaceous glands exist at all is not well understood. Some interesting theories have been postulated including roles for skin maintenance, immunological function and perhaps…
  • Long-term effects of parental divorce on mental health - A meta-analysis. [Journal Article]
    J Psychiatr Res 2019; 119:107-115Auersperg F, Vlasak T, … Barth A
  • The aim of this study was to estimate the long-term effects of parental divorce on their offspring's mental health as well as substance-based addiction. We performed a systematic literature search on PubMed, Medline, PsyINFO, PsyARTICLES and PsycNET for the time period from 1990 until March 2018 in English language. In total 54 studies were included in the meta-analysis resulting in 117 effect si…
  • Emerging targets for cough therapies; NK1 receptor antagonists. [Review]
    Pulm Pharmacol Ther 2019; :101853Badri H, Smith JA
  • Cough is mediated by vagal afferent fibres innervating the larynx and proximal airways. Pre-clinical studies suggest that vagal C fibres produce Substance P, one of the tachykinin family of neuropeptides, which has been shown to enhance cough via the neurokinin-1 (NK-1) receptor and studies in animal models have also shown that NK-1 antagonists are effective at blocking induced cough. In the past…
  • [Antiviral effect of «Kagocel» substance in vitro on influenza viruses H1N1, H1N1pdm09 and H3N2.] [Journal Article]
    Vopr Virusol 2019; 64(3):125-131Fediakina IT, Konopleva MV, … Nikitina NI
  • CONCLUSIONS: Effective suppression of the reproduction of influenza virus strains A(H1N1), A(Н1N1)pdm09 and A(H3N2) in the different sublines of MDCK cells with «Kagocel» was shown by the different methods. These results give the possibility to suggest that along with the ability to induce interferons, «Kagocel» can impact on the reproduction of influenza virus, but the further research is needed.«Kagocel» substance effectively inhibits the reproduction of influenza virus strains A(H1N1), A(Н1N1)pdm09 and A(H3N2) in vitro. At the same time, the selectivity index is quite high.
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