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(telomerictheory of aging)
416,856 results
  • Predictors of influenza vaccination among elderly: a cross-sectional survey in Greece. [Journal Article]
    Aging Clin Exp Res 2019Dardalas I, Pourzitaki C, … Bellali T
  • CONCLUSIONS: Only a small proportion of those over the age of 60 had received the influenza vaccine. This finding is worrying, as it indicates the impact that a future outbreak of seasonal influenza could exert upon vulnerable groups. There is an urgent need for further, better and more evidence-based information from healthcare professionals to achieve greater vaccination coverage in the community.
  • RIPK1 mediates TNF-induced intestinal crypt apoptosis during chronic NF-κB activation. [Journal Article]
    Cell Mol Gastroenterol Hepatol 2019Wong J, Garcia-Carbonell R, … Guma M
  • CONCLUSIONS: Contrary to common expectations, chronic NF-κB activation induced intestinal crypt apoptosis after TNF stimulation, resulting in severe mucosal erosion. RIPK1 kinase inhibitors selectively inhibited TNF's destructive properties while preserving its survival and proliferative properties, which do not require RIPK1 kinase activity. RIPK1 kinase inhibition could be a potential treatment for IBD.
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