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15 results
  • [Thought and method of reproductive toxicity research in traditional Chinese medicine]. [Review]
    Yao Xue Xue Bao 2014; 49(11):1498-503Han JY, Yan Y, … Li GQ
  • Reproductive toxicity research takes an important place in traditional Chinese medicine pre-clinical safety evaluation. Modern reproductive toxicity experiment includes drug-related miscarriage, fetal death, teratism, and adverse effects on fertility, genital system, embryonic development and fetus, which is different from contraindicated in pregnancy in traditional Chinese medicine theory. Now t…
  • Murine model for congenital CMV infection and hearing impairment. [Journal Article]
    Virol J 2011; 8:70Juanjuan C, Yan F, … Suhua C
  • CONCLUSIONS: The results suggest that the direct injection of MCMV into the placenta may efficiently cause fetal infection and disturb the intrauterine development of the fetus, and placental inoculation itself has no obvious adverse effects on offspring. The reduction in the number of spiral ganglion neurons and the ultrastructural lesions of the neurons may be the major cause of congenital CMV infection-induced progressive SNHL.
  • Teratism induced in the developing chick by RPR-V, an organophosphate. [Journal Article]
    Food Chem Toxicol 1992; 30(11):945-51Rao JV, Swamy AN, … Rahman MF
  • Fertile White Leghorn chicken eggs were injected on day 4 of incubation with 0, 0.25, 0.50 or 1.00 mg RPR-V/egg and opened on day 20 or allowed to hatch. The following parameters were examined: hatchability, growth and development, external malformations and skeletal deformities. As the dose was increased, the hatchability decreased, and the incidence of deformities increased. Staining of the ske…
  • Residence under an airport landing pattern as a factor in teratism. [Journal Article]
    Arch Environ Health 1978 Jan-Feb; 33(1):10-2Jones FN, Tauscher J
  • An analysis of all Los Angeles County birth records for the years 1970, 1971, and 1972 reveals a higher incidence of reportable birth defects in those census tracts lying wholly or partly within the 90 dbA loudness contours under the landing pattern at Los Angeles International Airport than in the rest of the County. While not proving that noise is responsible for the increase in teratism, these …
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