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56 results
  • Platelet inhibition by sodium nitroprusside, a smooth muscle inhibitor. [Journal Article]
    Blood 1976; 47(6):957-61Saxon A, Kattlove HE
  • The effects of sodium nitroprusside (N.P.), a pure smooth muscle inhibitor, on platelet function were studied. Platelet-rich plasmas (PRP) from normal controls and from patients receiving N.P. were studied in vitro for aggregation in response to adenosine diphosphate (ADP), epinephrine, and collagen. Platelet ADP release (release reaction) was also investigated. Normal platelets demonstrated mark…
  • Platelet aggregation induced by antilymphocyte serum. 2. Two modes of the aggregation mechanism. [Journal Article]
    Am J Clin Pathol 1976; 65(5):680-9Wang TY, Hussey CV, … Fobian JE
  • The ability to inhibit the release reaction was found to correlate well with the ability to inhibit aggregation in washed human platelets exposed to antilymphocyte serum (ALS). However, the primary mechanism that contributes to ALS-induced aggregation in unwashed platelets appeared to be different from that found in washed platelets. Prostaglandin E1 and other release inhibitors were less effecti…
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