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27,338 results
  • Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus. [Journal Article]
    Front Mol Neurosci 2020; 13:7Xu L, Zheng YL, … Ma JZ
  • Background: An imbalance between total training load and total recovery may cause overtraining (OT). The purpose of the present study was to verify the effects of OT on the expression of brain-derived neurotrophic factor (BDNF), its receptor tropomyosin receptor kinase B (TrkB) and p75 and the dynamic expression patterns of brain-specific miR-34a and miR-124 or inflammation-related miR-21 and miR…
  • Controversies in Fracture Healing: Early Versus Late Dynamization. [Journal Article]
    Orthopedics 2020; :1-9Schultz BJ, Koval K, … Cerynik DL
  • Dynamization of fracture fixation constructs provides early rigidity for primary bone healing and late motion for secondary healing. A review of laboratory, animal, and clinical studies investigating the impact, and optimal timing, of dynamization is limited by lack of standardization across studies. However, in animal models, dynamization improves histologic and biomechanical properties compared…
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