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1,052 results
  • Updating the evidence on drugs to treat overactive bladder: a systematic review. [Journal Article]
    Int Urogynecol J 2019; 30(10):1603-1617Hsu FC, Weeks CE, … McDonagh MS
  • CONCLUSIONS: New evidence confirms small, but clinically uncertain, differences among monotherapies and also between combination and monotherapy, regardless of statistical significance. While drugs mainly differed in incidence of dry mouth or constipation, none provided improved efficacy without increased harms.
  • Asymmetric Hydroarylation of Enones via Nickel-Catalyzed 5-Endo-Trig Cyclization. [Journal Article]
    Org Lett 2019; 21(15):5990-5994Qin X, Yao Lee MW, Zhou JS
  • A nickel-catalyzed reductive cyclization of enones affords a wide array of indanones in high enantiomeric induction. The reaction is featured with an unprecedented broad scope of substrates. The versatility of the new method is demonstrated in several short stereoselective syntheses of medically valuable (R)-tolterodine, parent and deuterated (+)-indatraline, and an antitumor natural product, (+)…
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