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3,398 results
  • Anti-Cryptococcal activity of a furanone derivative-antibiofilm and opsonophagocytic potential. [Journal Article]
    J Mycol Med 2020; :100924Rathore SS, Raman T, … Ramakrishnan J
  • Cryptococcus neoformans, an encapsulated fungal pathogen is evolving as a major threat to immune-compromised patients and rarely to healthy individuals also. The cell wall bound capsular polysaccharide, melanin pigment and biofilm formation are major virulence factors that are known to contribute to cryptococcal meningitis. In the present study, a furanone derivative, (E)-5-benzylidenedihydrofura…
  • Efficacy of CSF beta-D-glucan diagnostic testing for fungal meningitis: a systemic review. [Journal Article]
    J Clin Microbiol 2020Davis C, Wheat LJ, … Bahr NC
  • Background: Several case reports and cohort studies have examined the use of (1, 3) beta-D-glucan in cerebrospinal fluid to diagnose fungal meningitis. This systematic review aims to characterize the evidence regarding cerebrospinal fluid (1, 3) beta-D-glucan measurement to detect fungal meningitis.Methods: We searched PubMed for (1, 3) beta-D-glucan and each of several distinct fungi, cerebros…
  • Neurological worsening during treatment of an immunocompetent adult with Cryptococcus neoformans meningitis. [Case Reports]
    Med Mycol Case Rep 2020; 27:48-51Tanu S, Mihir M, … Annu A
  • Cryptococcal meningitis is being increasingly described in immunocompetent adults. We describe here a young immuncompetent adult of Indian origin from Ghana, West Africa with cryptococcal meningitis who had several ups and downs during his treatment. First he developed neurologic worsening due to premature transition from intensive to consolidation phase therapy. Subsequently he deteriorated due …
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