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5,160 results
  • Duplicated tramadol use in chronic low back pain: a nationwide cross-sectional study. [Journal Article]
    Basic Clin Pharmacol Toxicol 2019Koo H, Taek Lee M, … Jung SY
  • Tramadol is a weak opioid that is commonly used for chronic low back pain (LBP). Despite its effectiveness, duplicated use of tramadol, which may indicate abuse or dependence, may exacerbate potential adverse reactions. This population-based, cross-sectional study aimed to investigate the prevalence of duplication of tramadol and its associated factors among patients with LBP. From a Korean natio…
  • Integrating Carbon Nanomaterials with Metals for Bio-sensing Applications. [Journal Article]
    Mol Neurobiol 2019Sainio S, Leppänen E, … Laurila T
  • Age structure in most developed countries is changing fast as the average lifespan is increasing significantly, calling for solutions to provide improved treatments for age-related neurological diseases and disorders. In order to address these problems, a reliable way of recording information about neurotransmitters from in vitro and in vivo applications is needed to better understand neurologica…
  • Effects of Rescheduling Hydrocodone on Opioid Prescribing in Ohio. [Journal Article]
    Pain Med 2019Liu Y, Baker O, … Weiner SG
  • CONCLUSIONS: The 2014 federal rescheduling of hydrocodone was associated with declines in hydrocodone prescriptions in Ohio beyond what had already been occurring, and hydrocodone may have been briefly substituted with codeine. These results indicate that rescheduling did have a lasting effect but affected prescribing specialties variably.
  • Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis. [Review]
    Pharmacol Res 2019; :104447Pisanu C, Franconi F, … Agabio R
  • There are conflicting results about sex differences in the response to opioids for pain control and the role of potential influencing factors of these differences has not been investigated. We meta-analyzed differences and similarities between men and women in opioid response for pain control and investigated the potential influence of baseline pain intensity, age, body weight, and other factors …
  • A new clean-up approach for stomach content toxicological analysis. [Journal Article]
    Forensic Sci Int 2019; :109936Peres MD, Nascimento S, Pelição FS
  • Stomach content is a matrix often applied in post-mortem cases. It is especially important in oral intoxication cases. The main advantages are the usually high concentration of analytes and the lack of biotransformation process. Still, even with extensive sample preparation, the final extract is not always suitable for analysis. The aim of this study was to develop an alternative method using QuE…
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