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433 results
    J Zoo Wildl Med 2020; 50(4):947-955Maurer JK, Burton FJ, … Calle PP
  • Feces (n = 226; 2004-2015) from healthy captive and wild blue iguanas (Cyclura lewisi) from Grand Cayman, Cayman Islands, were examined for endoparasites. Parasites identified included Nyctotherus sp. and Entamoeba sp. cysts and trophozoites, trichomonad trophozoites, and oxyurid and trichostrongylid eggs. Endoparasites from postmortem examinations (n = 13) included adult and larval nematodes: Oz…
  • Paromomycin is superior to metronidazole in Dientamoeba fragilis treatment. [Journal Article]
    Int J Parasitol Drugs Drug Resist 2019; 11:95-100Burgaña A, Abellana R, … Perez-Porcuna TM
  • Dientamoeba fragilis is a trichomonad parasite of the human intestine that is found worldwide. However, the biological cycle and transmission of this parasite have yet to be elucidated. Although its pathogenic capacity has been questioned, there is increasing evidence that clinical manifestations vary greatly. Different therapeutic options with antiparasitic drugs are currently available; however…
  • Tetratrichomonas gallinarum granuloma disease in a flock of free range layers. [Journal Article]
    Vet Q 2019; 39(1):153-160Landman WJM, Gantois N, … Viscogliosi E
  • Granuloma disease in a flock of free range productive layers in the Netherlands in 2017 is described. The disease resembled granuloma outbreaks in layers caused by Tetratrichomonas gallinarum in 2013 and occurred in the same area in which the rearing farm considered as the source of the 2013 outbreaks was located. Between 55 and 84 weeks of age mortality was 20.3% (breeder's norm 3.9%). All dead …
  • Cadmium-dependent expression of a new metallothionein identified in Trichomonas vaginalis. [Journal Article]
    Biometals 2019; 32(6):887-899Netzahualcoyotzi BA, Puente-Rivera J, … Sánchez MEA
  • Metallothioneins (MTs) have been identified in a wide variety of organisms from bacteria to humans. The biological functions of these MTs have a key role in metalloregulatory metabolism and its expression is induced in response to different stimuli, particularly by divalent metal cations. Also, the action of MTs have been implicated in the survival of pathogens in presence of microbicidal concent…
  • 20S Proteasome as a Drug Target in Trichomonas vaginalis. [Journal Article]
    Antimicrob Agents Chemother 2019; 63(11)O'Donoghue AJ, Bibo-Verdugo B, … Eckmann L
  • Trichomoniasis is a sexually transmitted disease with hundreds of millions of annual cases worldwide. Approved treatment options are limited to two related nitro-heterocyclic compounds, yet resistance to these drugs is an increasing concern. New antimicrobials against the causative agent, Trichomonas vaginalis, are urgently needed. We show here that clinically approved anticancer drugs that inhib…
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