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(tritiated thymidine)
4,578 results
  • Inhibition of collagen production delays malignant mesothelioma tumor growth in a murine model. [Journal Article]
    Biochem Biophys Res Commun 2019; 510(2):198-204Abayasiriwardana KS, Wood MK, … Mutsaers SE
  • Malignant mesothelioma is an aggressive fibrous tumor, predominantly of the pleura, with a very poor prognosis. Cell-matrix interactions are recognized important determinants of tumor growth and invasiveness but the role of the extracellular matrix in mesothelioma is unknown. Mesothelioma cells synthesize collagen as well as transforming growth factor-beta (TGF-β), a key regulator of collagen pro…
  • Role of IL-35 in sublingual allergen immunotherapy. [Journal Article]
    J Allergy Clin Immunol 2019; 143(3):1131-1142.e4Shamji MH, Layhadi JA, … Durham SR
  • CONCLUSIONS: IL-35 and iTR35 cells are potential novel immune regulators induced by SLIT. The clinical relevance of SLIT can be underscored by restoration of protective iTR35 cells.
  • Use of the LLNA:BrdU-ELISA for Skin Sensitization Hazard Assessment. [Journal Article]
    Methods Mol Biol 2018; 1803:101-116Lehmann DM
  • Allergic contact dermatitis (ACD) continues to be an occupational and environmental health issue. Consequently, there is a need to employ predictive tests to reduce the incidence of skin sensitization leading to clinical manifestations of ACD. For more than a decade, the murine local lymph node assay (LLNA) has been the method of choice for the identification of skin sensitizers. While the origin…
  • Tritium internal dose estimation from measurements with liquid scintillators. [Journal Article]
    Appl Radiat Isot 2018; 137:18-22Pántya A, Dálnoki Á, … Pázmándi T
  • Tritium may exist in several chemical and physical forms in workplaces, common occurrences are in vapor or liquid form (as tritiated water) and in organic form (e.g. thymidine) which can get into the body by inhalation or by ingestion. For internal dose assessment it is usually assumed that urine samples for tritium analysis are obtained after the tritium concentration inside the body has reached…
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